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OpenTrials
Completed

NCT Number: NCT00407238

Corneal Barrier Function With Multi-Purpose Solutions

The purpose of this study is to evaluate the effect on epithelial barrier function of three emarketed multi-purpose solution applied to the human eye with hydrogel lenses as during normal regimen use.

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Key information

Conditions

Contact Lens Care

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Southern California College of Optometry

Fullerton, California, 92831, United States

About this study

The purpose of this study is to evaluate the effect on epithelial barrier function of three emarketed multi-purpose solution applied to the human eye with hydrogel lenses as during normal regimen use.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adapted daily soft contact lens wearers, at least 18 years of age, vision correctable to 20/40

Exclusion criteria

  • Ocular or systemic allergies, abnormalities of the cornea, active ocular infection, prior keratorefractive surgery, use of ocular medications

Treatment and study plan

Multi-purpose solutions (polyquaternium-1 and PHMB)

Device

Primary outcomes

  1. Ratio of fluorescein dye penetration rate of test eye vs. control

Secondary outcomes

  1. Corneal fluorescein staining

Sponsors and collaborators

Lead sponsor

Southern California College of Optometry at Marshall B. Ketchum University

Other

Collaborators

  • Alcon Research

Registry information

Official study title

Comparison of Human Corneal Barrier Function With Three Marketed Multi-Purpose Solutions

Important dates

Study start
2006
Study completion
2007
First posted
Dec 4, 2006
Registry last updated
Oct 23, 2007

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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