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Completed

NCT Number: NCT07360496

Core Endurance, Finger Grip Strength, Fatigue, and Hand Function in Patients With Rheumatoid Arthritis

This study investigated the relationships between core endurance, finger grip strength, fatigue, and hand function in patients with rheumatoid arthritis.

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Key information

About this study

The aim was to evaluate the level of RA activity and disease activity and to examine the differences between healthy controls and RA patients in terms of these results.

A total of 113 people participated in the study, including 75 patients (57 women and 18 men; mean age: 48.65±12.53) diagnosed with RA (moderate and high levels of disease activity) aged 18-65 years and 38 healthy control group members (28 women and 10 men; mean age: 45.11±10.6).

In the evaluation, finger grip strength measurements (double grip, lateral grip, three-point grip) were done using a pinchmeter. In the kor endurance measurement, the patient was asked to lift their knees off the ground in a crawling position by contracting their kor muscles and keeping their waist at a certain distance, and the time they maintained the position was recorded. Hand function with SACRAH (Skor For Assessment And Quantification Of Chronic Rheumatic Affections Of The Hands), fatigue severity with FSS (Fatigue Severity Skor) and physical activity level with FIT Index (Frequency-Intensity-Time) were measured.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

  • RA Group Inclusion Criteria:
  • Diagnosed with RA according to ACR/EULAR criteria
  • Between 18-65 years of age
  • Willing to participate in the study

RA Group Exclusion Criteria:

  • Having any chronic disease other than RA
  • Having another musculoskeletal disease
  • Having adaptation problems and psychiatric illnesses that would impair participation in the study
  • Having hearing loss that would impair communication
  • Having severe vision loss
  • Having another rheumatic disease other than RA
  • Having any uncontrolled cardiopulmonary disease
  • Having a serious deformity or severe pain in the extremities or trunk that would prevent taking a crawling position (7 or higher on a 10-point numerical pain scale) (being present)
  • Hand deformity or pain severe enough to prevent finger grip strength measurements
  • History of any serious trauma or injury within the last 6 months
  • Changes in medication used for RA within the last 3 months
  • Receiving physiotherapy or other treatment other than medication
  • History of musculoskeletal surgery (trunk, extremities)
  • Being pregnant or breastfeeding

Health Controls Inclusion Criteria:

  • Being between 18-65 years of age
  • Voluntary participation in the study Health Controls Exclusion Criteria: ● Having any diagnosed illness
  • Having a history of trauma

Treatment and study plan

Primary outcomes

  1. Core endurance

    Time frame: December 2022-September 2023

    Modified prone plank. This test began with a crawling position, and the participant was instructed to lift their knees off the ground and maintain that position.

Secondary outcomes

  1. Finger grip strength

    Time frame: December 2022-September 2023

    Finger grip strength (double grip, lateral grip, three-point grip) was measured using a pinchmeter.

  2. Hand function

    Time frame: December 2022-September 2023

    Hand function was measured with SACRAH (Score For Assessment And Quantification Of Chronic Rheumatic Affections Of The Hands). SACRAH is a scale consisting of 23 questions. Questions 1-17 assess hand function, questions 18-19 assess stiffness, and questions 20-23 assess pain. Scoring is done on a scale of 0-100, and the higher the score, the worse the outcome.

  3. Fatigue severity

    Time frame: December 2022-September 2023

    Fatigue severity was determined using FSS (Fatigue Severity Score).It contains 9 questions, each scored between 0-7. A total FSS score of 6.1 or higher indicates chronic fatigue.

  4. Physical activity level

    Time frame: December 2022-September 2023

    Determined with FIT Index (Frequency-Intensity-Time).The maximum FIT index score is 100. Higher FIT scores indicate high levels of physical activity.

Sponsors and collaborators

Lead sponsor

Cumhuriyet University

Other

Registry information

Official study title

Investigation of the Relationships Between Core Endurance, Finger Grip Strength, Fatigue, and Hand Function in Patients With Rheumatoid Arthritis

Important dates

Study start
2022
Primary completion
2023
Study completion
2024
First posted
Jan 22, 2026
Registry last updated
Jan 22, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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