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OpenTrials
Active, Not Recruiting

NCT Number: NCT03623074

Control of Myopia Using Novel Spectacle Lens Designs

Randomized, controlled, multisite, subject-and observer-masked, 3-arm parallel group clinical trial of 36-month duration to evaluate the safety and efficacy of a novel spectacle lens design in reducing the progression of juvenile myopia.

Active, Not Recruiting

This study is active but is not currently recruiting participants.

Key information

Conditions

Juvenile Myopia Eye Diseases Myopia Refractive Errors

Age range

6 year–10 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Center for Ocular Research & Education, School of Optometry, University of Waterloo School of Optometry & Vision Science, Waterloo, Ontario, Canada

Loading trial locations.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Children 6-10 years of age (day prior to 10th birthday) at time of informed consent/assent
  • SER error between -0.75 and -4.50 D
  • SER power between the two eyes must be less than or equal to 1.50 D
  • Willingness to participate in the trial for 3 years without content lens wear

Exclusion criteria

  • Previous or current use of contact lenses
  • Previous or current use of bifocals, progressive addition spectacles lenses
  • Previous or current use of myopia control treatment
  • Astigmatism worse then -1.25 DC in either eye

Treatment and study plan

Novel spectacle lens design

Device

Use of lenses may reduce the rate of progression of juvenile myopia

Spectacle lenses

Device

Use of lenses may reduce the rate of progression of juvenile myopia

Primary outcomes

  1. Axial length

    Time frame: 36 Months

    Change in axial length from baseline

  2. Spherical equivalent refraction

    Time frame: 36 Months

    Change in spherical equivalent refraction from baseline

Sponsors and collaborators

Lead sponsor

SightGlass Vision, Inc.

Industry

Registry information

Official study title

Efficacy and Safety Study of Novel Spectacle Lens Designs to Control of Myopia

Acronym: CYPRESS

Important dates

Study start
2018
Primary completion
2022
Study completion
2026
First posted
Aug 9, 2018
Registry last updated
May 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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