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NCT Number: NCT03866018

Contribution of Physical Activity to Self-esteem and Motivation in Older Adults With Minor to Major Cognitive Disorders Such as Alzheimer's Disease or Related Disorders

Alzheimer's disease is the leading cause of dementia in people over 60 years of age. It is characterized by a decline in memory, learning ability and other cognitive domains (language, gnosis, praxis, attention), with a gradual progression of cognitive and behavioral symptoms. Because of the difficulties it causes in carrying out daily living activities, it has a very significant impact on the autonomy of patients suffering from it.

To date, there are various non-drug strategies available to manage these difficulties. Thus, in recent years, more and more studies have shown the benefits that can be gained by several patients care including physical activity, on cognitive function and general quality of life of the elderly people without cognitive impairment but also for patients suffering from Alzheimer's disease or a related pathology.

The objective of this study is to evaluate the effectiveness of adapted physical activity on self-esteem and motivation in patients with neurocognitive disorders. Stimulation groups are proposed within the Claude Pompidou Institute. Within these groups we offer an adapted physical activity program that we have developed in our department. More specifically, it is a study that aims to evaluate the impact of physical activity on the self-esteem and motivation of patients who perform these exercises for 12 weeks, at the rate of one hour per week.

The interest of this study lies in the validation of the effectiveness of such patient care, which would make it possible to promote its dissemination and strengthen the accessibility of this type of non-drug management to elderly people suffering from neurocognitive disorders.

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Key information

Age range

60 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Institut Claude Pompidou - Centre Mémoire de Ressources et de Recherche du CHU de Nice

Nice, 06100, France

About this study

Alzheimer's disease is the leading cause of dementia in people over 60 years of age. It is characterized by a decline in memory, learning ability and other cognitive domains (language, gnosis, praxis, attention), with a gradual progression of cognitive and behavioral symptoms. Because of the difficulties it causes in carrying out daily living activities, it has a very significant impact on the autonomy of patients suffering from it.

To date, there are various non-drug strategies available to manage these difficulties. Thus, in recent years, more and more studies have shown the benefits that can be gained by several patients care including physical activity, on cognitive function and general quality of life of the elderly people without cognitive impairment but also for patients suffering from Alzheimer's disease or a related pathology.

The objective of this study is to evaluate the effectiveness of adapted physical activity on self-esteem and motivation in patients with neurocognitive disorders. Stimulation groups are proposed within the Claude Pompidou Institute. Within these groups we offer an adapted physical activity program that we have developed in our department. More specifically, it is a study that aims to evaluate the impact of physical activity on the self-esteem and motivation of patients who perform these exercises for 12 weeks, at the rate of one hour per week.

The interest of this study lies in the validation of the effectiveness of such patient care, which would make it possible to promote its dissemination and strengthen the accessibility of this type of non-drug management to elderly people suffering from neurocognitive disorders.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Male or Female ≥ 60 years old
  • MMSE score between 4 and 26 / 30
  • Diagnosis of minor to major NeuroCognitive Disorder of the Alzheimer type or multiple etiology;
  • Subject without a major hearing or visual impairment;
  • Subject not presenting any contraindications to the practice of adapted physical activity;
  • Subject affiliated to Social Security System;
  • Signing informed consent

Exclusion criteria

  • < 60 years
  • Medical indications: Recent or unstable cardiovascular events: ECG changes, unstable angina, uncontrolled arrhythmia, 3rd degree BAV, acute heart failure.
  • MMSE score < 4
  • Subject already engaged in appropriate physical activity
  • Subject with a perceptual disorder (AMD, deafness...)
  • Subject with a motor disability
  • Subject under guardianship, curatorship or safeguard of justice
  • Persons deprived of their liberty (administrative or judicial)

Treatment and study plan

adapted physical activity

Other

12 sessions of one hour of adapted physical activity.

Primary outcomes

  1. Improvement of patient self-esteem

    Time frame: At 4 months

    Rosenberg self-esteem scale

  2. Improvement of patient motivation

    Time frame: At 4 months

    EAD scale

  3. Improvement of patient apathy

    Time frame: At 4 months

    Apathy inventory

Secondary outcomes

  1. Quantitative assessment of physical activity

    Time frame: At 4 months

    questionnaire for caregivers

  2. Patient satisfaction

    Time frame: At 4 months

    satisfaction questionnaire

Sponsors and collaborators

Lead sponsor

Centre Hospitalier Universitaire de Nice

Other

Registry information

Acronym: APAMA

Important dates

Study start
2019
Primary completion
2019
Study completion
2020
First posted
Mar 7, 2019
Registry last updated
Jun 16, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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