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OpenTrials
Completed

NCT Number: NCT02039102

Contraceptive Use and Respiratory Conditions Among Scottish Women

Studies examining the sex differences in the epidemiology and morbidity patterns of asthma show that the rates of disease severity, healthcare utilisation, and poor quality of life are considerably higher in women than in men, and this has been attributed to endogenous and exogenous sex hormonal factors. Studies examining the impact of use of hormonal contraceptives on the risk of asthma and asthma-related conditions are few, yet findings are conflicting.

In the present study, the investigators utilize data from the Scottish Health Survey, a national representative sample, to investigate the associations between current use of hormonal contraceptives and the prevalence of self-reported doctor-diagnosed current asthma and wheezing symptoms in Scottish women. The investigators hypothesize that while current use of any hormonal contraceptives and combined oral pills are associated with higher prevalence of asthma and asthma outcomes, current use of progesterone-only contraceptives is not associated with asthma. A secondary aim of the current study is to examine whether there is evidence of any biological interaction between use of hormonal contraceptives and BMI in relation to the risk of asthma and asthma outcomes.

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Key information

Age range

16 year–45 year

Sex eligibility

Female

Study type

Observational

Primary location

University of Ediburgh

Edinburgh, United Kingdom

Who can participate

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Non-pregnant
  • Woman
  • 16-45 years old

Exclusion criteria

  • Pregnant
  • Man
  • Younger than 16 years or older than 45 years old

Treatment and study plan

Primary outcomes

  1. Self-reported doctor-diagnosed current asthma

    Time frame: During the past 12 months

Secondary outcomes

  1. Self-reported wheezing symptom

    Time frame: During the past 12 months

  2. Self-reported current treatment for asthma/wheeze

    Time frame: During the past 12 months

Sponsors and collaborators

Lead sponsor

University of Edinburgh

Other

Registry information

Official study title

Use of Hormonal Contraceptives in Relation to Asthma and Wheezing Disorders in Scottish Women: a Population-based Cross-sectional Survey

Important dates

Study start
2013
Primary completion
2018
Study completion
2018
First posted
Jan 17, 2014
Registry last updated
Jun 21, 2021

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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