Continuous Glucose Monitoring and Inflammation in Nondiabetic and Diabetic Patients Undergone Hemodialysis

Evaluation of different glycemic variations between the dialysis period and non-dialysis period in two groups: nondiabetic and diabetic patients undergone two different hemodialysis methods. Thirty-six patients, males and females, aged 50-80 years, with end stage renal disease (ESRD) will undergo hemodialysis and continuous glucose monitoring (CGM). The investigators will evaluate also inflammation markers before and after the different hemodialysis methods.

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Key information

Conditions

Diabetes Chronic Disease Diabetes Mellitus Disease Attributes End Stage Renal Disease Endocrine System Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Glucose Metabolism Disorders Kidney Diseases Kidney Failure, Chronic Male Urogenital Diseases Metabolic Diseases Nutritional and Metabolic Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Renal Insufficiency Renal Insufficiency, Chronic Urogenital Diseases Urologic Diseases

Age range

50 year–80 year

Sex eligibility

All sexes

Study type

Observational

Primary location

IRCCS Policlinico San Matteo

Pavia, 27100, Italy

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

patients with or without diabetes mellitus
ESRD
undergone hemodialysis
males and females aged 50-80

Exclusion criteria

tumors
chronic inflammation diseases
AMI
acute pulmonary diseases

Treatment and study plan

Continuous glucose monitoring (CGM)

Device

CGM allocated one time for 3 days

Primary outcomes

-Hemodialysis tolerability -Hypoglycemia numbers -Hyperglycemia numbers -Inflammation markers

Time frame: before and after each procedure

Secondary outcomes

variations of glycemia during the night; insulin-sensitivity

Time frame: at the beginning of the first hemodialysis and at the end of the second hemodialysis

Sponsors and collaborators

Lead sponsor

University of Pavia

Other

Registry information

Important dates

Study start: 2009
Primary completion: 2014
Study completion: 2014
First posted: Jan 14, 2010
Registry last updated: May 24, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed