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Completed

NCT Number: NCT00695084

Constraint-Induced (CI) Movement Therapy for Progressive Multiple Sclerosis (MS)

This trial will evaluate whether progressive multiple sclerosis associated with hemiparesis may benefit from Constraint-Induced Movement Therapy.

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Key information

Conditions

Multiple Sclerosis Autoimmune Diseases Autoimmune Diseases of the Nervous System Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Immune System Diseases Nervous System Diseases

Age range

21 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 1

Primary location

University of Alabama at Birmingham

Birmingham, Alabama, 35249, United States

About this study

Constraint-Induced Movement Therapy was developed to treat stroke hemiparesis. Due to the similarity between multiple sclerosis and stroke in terms of chronic motor deficit, this trial will attempt to determine whether multiple sclerosis may benefit similarly from Constraint-Induced Movement Therapy.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Chronic upper extremity motor deficit due to multiple sclerosis

Exclusion criteria

  • Relapse within 3 months of planned enrollment.

Treatment and study plan

Constraint-induced movement therapy

Behavioral

Intensive practice with the hemiparetic arm for 30 contact hours

Other names: CI Therapy

Primary outcomes

  1. Improvement on the Motor Activity Log

    Time frame: One year

Secondary outcomes

  1. Improvement on the Wolf Motor Function Test

    Time frame: Pre to post-treatment

Sponsors and collaborators

Lead sponsor

National Multiple Sclerosis Society

Other

Registry information

Official study title

Constraint-Induced Movement Therapy Trial for Progressive Multiple Sclerosis

Important dates

Study start
2007
Primary completion
2008
Study completion
2008
First posted
Jun 11, 2008
Registry last updated
Jun 11, 2008

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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