Constitution of ex Vivo Ovarian Tumor Models for the Validation of the Interest of Innovative Therapies and the Search for Tumor or Circulating Biomarkers Predictive of Treatment Response

Development of ex vivo models of ovarian cancer, fallopian tubes or peritoneum.

Completed

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Key information

Conditions

Ovarian Cancer Adnexal Diseases Endocrine Gland Neoplasms Endocrine System Diseases Female Urogenital Diseases Female Urogenital Diseases and Pregnancy Complications Genital Diseases Genital Diseases, Female Genital Neoplasms, Female Gonadal Disorders Neoplasms Neoplasms by Site Ovarian Diseases Ovarian Neoplasms Urogenital Diseases Urogenital Neoplasms

Age range

18 year and older

Sex eligibility

Female

Study type

Observational

Primary location

Centre François BACLESSE

Caen, France

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patient over 18 years old.
Patient with ovarian cancer, carcinoma of the fallopian tubes, or histologically proven peritoneum. All FIGO stages are accepted for the study.
Patient to be managed by surgery (laparoscopy and / or laparotomy).

Exclusion criteria

Pregnant woman
Persons deprived of liberty or guardianship (including curatorship)
History of any other clinically active malignancy in the last 5 years prior to inclusion

Treatment and study plan

collection of blood, urine, tumor and ascite samples

Genetic

collection of blood, urine, tumor and ascite samples during ovarian surgery

Primary outcomes

Rates of exploitable ex vivo tumor, blood and urine samples for performing predictive tests

Time frame: Collection of blood, urine, tumor and ascite samples at the time of ovarian surgery

Number and quality of tumor, blood and urine samples that can be used to perform predictive tests of the response to treatment

Sponsors and collaborators

Lead sponsor

Centre Francois Baclesse

Other

Registry information

Acronym: OVAREX

Important dates

Study start: 2019
Primary completion: 2025
Study completion: 2025
First posted: Feb 5, 2019
Registry last updated: Aug 8, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed