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Completed

NCT Number: NCT06870864

Conservative Versus Operative Management in Adhesive Intestinal Obstruction

This study aims to evaluate the role of Conservative management in patients with adhesive Intestinal Obstruction Regarding the selection criteria of the patients, duration of conservative route, success rate, and recurrence of adhesions and avoiding the surgical route complications.

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Key information

Age range

6 year–70 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Faculty of Medicine, Sohag University

Sohag, Egypt

About this study

Adhesive Intestinal Obstruction is very common and represents a serious life threatening condition, which can be caused by congenital band, following abdominal surgeries and other medical conditions like tuberculosis.

The management options for adhesive intestinal obstruction (AIO) could be operative treatment (open-laparoscopy) or non-operative (conservative management) according to many reasons.

Some reports indicate that the operative management for adhesive Intestinal obstruction lead to further adhesions in the future in addition to other possible complications (anaesthetic - iatrogenic injury during adhesolysis - wound site infections - illius-long hospital stay).

The Conservative route is recommended in all patients except those with signs of peritonitis, strangulation, or bowel ischemia which would have been diagnosed during physical examination and imaging.

A few studies compared the advantages, safety, and less complications of Conservative versus operative management. Therefore, this study will be conducted on patients with adhesive Intestinal Obstruction to compare the effectiveness of Conservative versus operative management regarding the selection criteria for the patients, the duration of the Conservative route, things to be done and what need to be observed during the conversation time.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 6-70 years.
  • Both sexes.
  • Complete \\ Partial adhesive Intestinal Obstruction, with CT Abdomen and pelvis with oral and IV Contrast.

Exclusion criteria

  • Patients with signs of Strangulation
  • Patients with signs of peritonitis.
  • Patients with signs of bowel ischemia
  • Failure of Conservative management for more than 72 hours.
  • Vitally unstable patients
  • Patients with comorbidities which need rapid interventions.

Treatment and study plan

Primary outcomes

  1. X-Ray Changes

    Time frame: 72 Hours

    Daily Chest Abdomen X-ray Erect copies to evaluate the improvement of the Intestinal Obstruction through evaluation of the X-ray findings (Air fluid levels).

  2. Passability Status

    Time frame: 72 Hours

    Daily history taking records and per rectal examination findings to evaluate the passability status (stool /flatus)

  3. Hospital Stay Duration

    Time frame: from 3 to 5 days.

    The Conservative management in patients with adhesive Intestinal Obstruction will avoid them the surgical route which requires long hospital stay postoperative

  4. Vomiting

    Time frame: 72 Hours

    Frequency and severity of vomiting will be collected to help in prognosis prediction

  5. Abdominal Signs

    Time frame: 72 Hours

    Data collected about Daily abdominal examination findings (Distention, Intestinal sounds, abdominal pain and Per rectal examination).

Secondary outcomes

  1. Recurrence of Attacks

    Time frame: two years previous the onset of the current attack. (During the last two years before the admission)

    past history about the previous attacks of the adhesive Intestinal Obstruction

  2. Past Surgical History

    Time frame: two years previous the onset of the current attack. (During the last two years before the admission)

    Detailed history about the previous operations to determine the relationship between different operations and adhesive Intestinal Obstruction

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Role of Conservative Management in Adhesive Intestinal Obstruction Versus Operative Management

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Mar 11, 2025
Registry last updated
Mar 11, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.