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NCT Number: NCT07519993

Conservative Management of Placenta Accreta Spectrum Using Kasr Al-Ainy Technique With or Without Hayman Sutures

This study evaluates whether adding Hayman sutures in the conservative Management of Placenta Accreta Spectrum Using Kasr Al-Ainy Technique reduces intraoperative blood loss and improves outcomes

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Key information

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age 18-40 years
  • Antenatal PAS diagnosis confirmed by TAS/TVS/Doppler
  • Eligible for conservative Kasr Al-Ainy surgery
  • Singleton pregnancy
  • Written informed consent

Exclusion criteria

  • Multiple pregnancy
  • Uterine fibroids
  • Previous cesarean myomectomy
  • Cervical accreta
  • Extensive parametrial or bladder invasion requiring hysterectomy
  • Known coagulopathy or uncorrected bleeding disorder.
  • Severe medical comorbidities rendering the patient unfit for major surgery under general anesthesia (e.g., severe cardiac or pulmonary disease)
  • Medical disorders as HTN and DM
  • Patient refusal

Treatment and study plan

Kasr Al-Ainy Technique Alone

Procedure
  • Vascular Ligation: Bilateral uterine artery tying at high and low levels.
  • Compression Sutures: Anterior and posterior cervicovaginal stitches for hemostasis.
  • Segmental Resection: Excision of invaded myometrium and placental tissue.
  • Dual-Layer Repair: Myometrial approximation followed by reinforcing imbricating sutures.
  • Final Hemostasis: Confirmation of bleeding control prior to abdominal closure.

Kasr Al-Ainy Technique + Hayman Sutures

Procedure
  • Vascular Ligation: Bilateral uterine artery tying at high and low levels.
  • Compression Sutures: Anterior and posterior cervicovaginal stitches for hemostasis.
  • Segmental Resection: Excision of invaded myometrium and placental tissue.
  • Dual-Layer Repair: Myometrial approximation followed by reinforcing imbricating sutures.
  • Final Hemostasis: Confirmation of bleeding control prior to abdominal closure.
  • Application of Hayman vertical compression sutures

Primary outcomes

  1. Intra-operative estimated blood loss

    Time frame: During operation

Study contacts

Contact information is provided by the study sponsor or research team.

Abdallah Mousa, M.D.

CONTACT

[email protected]

+20 1277664430

Asmaa Ali

CONTACT

[email protected]

+20 1222338010

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 9, 2026
Registry last updated
Apr 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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