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NCT Number: NCT07343011

Conjunctival Transpositional Surgery for Primary Pterygium

This prospective single-arm interventional study evaluates the recurrence rate and functional outcomes following conjunctival transpositional pterygium surgery without bare sclera formation. The technique involves mobilization and transposition of the pterygium tissue while preserving Tenon's layer and avoiding adjunctive therapies.

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Key information

Conditions

Pterygium of the Conjunctiva and Cornea Corneal Diseases Eye Diseases

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Alzahra Eye Hospital, Zahedan University of Medical Sciences

Zahedan, Sistan and Balochistan, Iran

Location status: Recruiting

Location contact

Mohammed Arish, MD, FRCS

CONTACT

[email protected]

09151419155

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Adults aged 18 years or older
  • Primary pterygium involving the cornea
  • Ability to provide informed consent

Exclusion criteria

  • Recurrent pterygium
  • Previous ocular surface surgery
  • Active ocular infection or inflammation
  • Severe ocular surface disease

Treatment and study plan

Conjunctival Transpositional Pterygium Surgery

Procedure

A conjunctival incision was created at the upper and lower limbus to allow adequate tissue mobilization. The pterygium tissue is dissected off the corneal surface without complete excision or creation of a bare sclera defect. The fibrovascular tissue is mobilized and transposed inferiorly within the subconjunctival plane and secured with absorbable sutures. Tenon's tissue is preserved, and no adjunctive therapy is used.

Primary outcomes

  1. Pterygium Recurrence

    Time frame: 12 months

    Recurrence is defined as fibrovascular regrowth toward the cornea or surgical failure.

Secondary outcomes

  1. Visual Acuity

    Time frame: 12 months

    Change in visual acuity measured in logMAR units.

  2. Refractive Astigmatism

    Time frame: 12 months

    Change in refractive astigmatism measured as cylindrical power in diopters.

Study contacts

Contact information is provided by the study sponsor or research team.

Mohammed Arish, MD, FRCS

CONTACT

[email protected]

09151419155

Sponsors and collaborators

Lead sponsor

Zahedan University of Medical Sciences

Other

Registry information

Official study title

Conjunctival Transpositional Pterygium Surgery: A Prospective Single-Arm Interventional Study

Important dates

Study start
2025
Primary completion
2026
Study completion
2027
First posted
Jan 15, 2026
Registry last updated
Jan 15, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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