Confrontation Phenotypes and Genotypes of Epithelial Odontogenic Tumors of the Jaws

This is an observational study with retrospective and prospective parts. In retrospective part be included the Patients followed between 1992 and January 2011.

In prospective part will follow the Patients will be included after the starting of study.

There are 2 centers :

• st center is in the service of Stomatology and Maxillofacial Surgery in the Pitie Salpetriere Hospital.
• nd center is in the service of Maxillofacial Surgery in hospital Armand Trousseau.

Number of patients include in the part retrospective :

Center N°1-300adults Center N°2-90childrens

Number of patients include in the part prospective :

Center N°1- 90 Center N°2- 30

Duration of study is 3 years Duration of inclusion is 32 months Each patient will be followed for 4 months and for further up to 3 years from the first patient included.

We envision a next circuit : obtaining consent, preoperative consultation,surgery, postoperative consultation N°1, postoperative consultation N°2, genetics consultation and monitoring of patients in 6;12;18;24 months from surgery of tumor and limited in 3 years from th 1st patient included.

Inclusion criteria

• Patient with an osteolytic lesion of the jaws
• Patient with epithelial odontogenic tumor:

keratocysts ameloblastoma Pindborg tumor or calcifying (ESWT) Epidermoid (Squamous Odontogenic Tumor SOT) Clear cell (Clear Odontogenic Tumor Cells CCOT)

• Patient monitoring in the period 1992 to January 2011 at the Trousseau Hospital (children) or at the Pitie Salpetriere (adult)
• Patient aged 5 years or more
• Adult patient who had signed informed consent
• Holders of parental authority of minor patient were informed and signed consent

Non inclusion criteria

• Patient with an osteolytic lesion of dental origin inflammatory (adjacent teeth decayed, non-living mortified)
• Patient with a cyst fissure (nasopalatine, symphyseal or globulomaxillary)
• Patient with arteriovenous malformation, vascular
• Patient with cons-indication to MRI
• Patient not affiliated with a social security scheme (beneficiary or assignee)
• Pregnant woman
• Patient in his history of hypersensitivity to salts of gadolinium
• Patient receiving a measure of legal protection