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Completed

NCT Number: NCT01130389

CONDOR Study of Osteonecrosis of the Jaws (TMJ)

The purpose of this study was to examine risk factors for osteonecrosis of the jaw (ONJ), including the possible association with bisphosphonates (BPs). This study used the research infrastructure from the three NIDCR-funded dental practice-based research networks (DPBRN, PEARL, PRECEDENT). De-identified data from the DPBRN were merged with comparable de-identified data from PEARL and PRECEDENT to form a single trans-PBRN data set used for analysis.

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Key information

Conditions

Osteonecrosis of the Jaw

Age range

40 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

University of Alabama at Birmingham, Birmingham, Alabama, United States

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About this study

The aims of this study were to (1) test the hypothesis that (BP) treatment is a risk factor for (ONJ); (2) to test the hypothesis that dental diseases (particularly periodontal disease), and invasive dental procedures such as dental extractions are true risk factors for (ONJ).

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • participants directly involved in this study were patients of dentists from the dental practice based research networks (DPBRN, PEARL, PRECEDENT).

Exclusion criteria

  • participants with a history of sickle cell anemia
  • participants with a history of external severe trauma to the jaws

Sponsors and collaborators

Lead sponsor

Dental Practice-Based Research Network

Network

Collaborators

  • HealthPartners Institute
  • Kaiser Permanente
  • National Institute of Dental and Craniofacial Research (NIDCR)
  • Permanente Dental Associates Group, Oregon

Registry information

Official study title

Trans-PBRN Case-control Study of Osteonecrosis of the Jaws

Important dates

Study start
2007
Primary completion
2008
Study completion
2008
First posted
May 26, 2010
Registry last updated
Jun 16, 2011

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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