Concordance and Discordance in the Assessment of Volume Status in Home Dialysis Patients: A Comparison of Modified Medical Research Council Dyspnea Scale, Physical Exam, and Point of Care Ultrasound (POCUS)

This study involves collecting information about you or from you. If you agree to be in the study, you will do your best to complete the following:

• Provide consent for us to review your medical records, including those from your dialysis center.
• The entire study visit will last for approximately 30-60 minutes including checking blood pressure, weight, questionnaire, doctor's visit and ultrasound
• We will measure blood pressure and weight if it's a part of your routine visit
• You will be given a questionnaire called modified medical research council dyspnea scale which includes only 1 question and anticipated to take less than a minute to answer
• After this, you will have your visit with your kidney doctor as usual. The doctor will assess how much excess fluid you might have by listening to your lungs and checking for swelling in your legs. They will not be given the results of the above survey.

After this, you'll go to a private room for the ultrasound procedure:

You'll lie flat on your back, and we'll expose your chest. A small amount of gel will be put on your skin, and we'll use a handheld ultrasound device to lightly press on your chest. We'll scan eight specific areas on your chest (four on each side) to look for something called "B-lines," which can show if there's extra fluid in your lungs. This ultrasound part of the visit should only take about 10 to 15 minutes in total.

Care will be taken to expose only the area being scanned. A chaperone (someone else in the room) will be present for all female patients. All male patients will be asked if they want a chaperone. If they say yes, a chaperone will be present during the ultrasound procedure. After the ultrasound, we'll wipe off the gel with a cloth, and you'll be ready to leave the room.

We expect the entire study from enrollment to the completion of data collection for all subjects, to last 9 months. However, your study visit will last only for 30-60minutes.

Inclusion criteria

• Age: Greater than 18 years.
• Diagnosis: End-stage kidney disease (ESKD).
• Treatment: Receiving home dialysis, either peritoneal dialysis (PD) or home hemodialysis (HHD).
• Duration of Home Dialysis: At least three months on home dialysis.

Exclusion criteria

• Consent: Inability to provide informed consent.
• Inclusion Criteria: Not meeting any of the inclusion criteria.
• Pregnancy.
• Urgent-Start PD.
• Any other obvious cause of shortness of breath not related to volume overload including but not limited to pneumonia, pneumothorax, advanced COPD and Interstitial lung disease.