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NCT Number: NCT07547709

Computerized Cognitive Behavioral Therapy-Depression (cCBT-D) for Caregivers of Veterans

Preliminary evaluation a caregiver cCBT-D protocol, including changes in psychosocial functioning and mental health symptoms as well as perceptions of feasibility, acceptability, and safety.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

About this study

We will pilot a tailored cCBT-D course (current version is Veteran focused; tailored version currently in development and to be submitted in a future amendment with minor changes to language and examples) is comprised of 12 online sessions. Sessions all have a similar structure that includes: 1) Weekly symptom ratings; 2) Review of practice assignments completed since last session; 3) Presentation of new material; and 4) Practice assignments to be completed in the coming week. Individuals can complete assignments within the course website or by printing out the worksheets. Their course "dashboard," which they see each time they log into the course, allows them to review past and upcoming course activities, read information about skills, and make notes about what was learned.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Individual aged between 18 and 65
  • Currently serving as a formal (i.e., designated as a legal caretaker [e.g., legally authorized representative of medical care]) or informal (e.g., providing caretaking duties but not formally designated by a legal body) caretaker to a Veteran.
  • Mild to moderate depressive symptoms, as determined by the PHQ-9 (score of 5-14)
  • Reliable access to a computer/tablet and the internet
  • Ability to provide informed consent

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Exclusion criteria

  • PHQ-9 score below 4 or 15 and above 2. Active alcohol or substance use disorder, excluding Cannabis dependence, as determined by screening or electronic medical record 3. Identification of active psychosis or bipolar disorder, as determined via screening or electronic medical record 4. Severe cognitive impairment precluding the ability to provide informed consent

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Treatment and study plan

cCBT-D for Caregivers

Behavioral

The cCBT-D course is compromised of approximately 12 online sessions. Sessions all have a similar structure that includes: 1) Weekly symptom ratings; 2) Review of practice assignments completed since last session; 3) New material; and 4) Practice assignments to be completed in the coming week. Individuals can complete assignments within the course website or by printing out the worksheets. Their course "dashboard," which they see each time they log into the course, allows them to review past and upcoming course activities, read information about skills, and make notes about what was learned. The cCBT-D course uploaded into the initial submission is one developed for Veterans. We are currently in the process of updating this course for Veteran caregivers (e.g., updates to wording for caregivers; including updating examples). We will upload this updated version in a future example (prior to initiating any interventional procedures). Finally, although this project is anticipated to be min

Primary outcomes

  1. Client Satisfaction Questionnaire (CSQ)

    Time frame: Post-Intervention - After participation in online intervention - up to 14 weeks after consent

    Satisfaction with the intervention

Study contacts

Contact information is provided by the study sponsor or research team.

Lisa Brenner, Ph.D.

CONTACT

[email protected]

720-315-6454

Sponsors and collaborators

Lead sponsor

VA Eastern Colorado Health Care System

Fed

Collaborators

  • Denver Research Institute
  • Face the Fight

Registry information

Important dates

Study start
2026
Primary completion
2026
Study completion
2026
First posted
Apr 23, 2026
Registry last updated
Apr 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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