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NCT Number: NCT06375083

Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression

This study plans to learn more about the use of one of two self-guided online cognitive behavioral therapy courses. One is focused on symptoms of depression and one is focused on history of suicidal thoughts and behaviors.

Recruiting

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Key information

Conditions

Suicide Behavior Behavioral Symptoms Depression Self-Injurious Behavior

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

About this study

Based on previous work with other computerized CBT (cCBT) interventions (e.g., cCBT-D), which has found that cCBT has similar effectiveness to traditional CBT, members of the team along with Veterans Health Administration (VHA) leaders have developed computerized cCBT-SP and cCBT-D courses that will be ready for safety, feasibility, and acceptability testing. If proven to be feasible, safe, and effective, these courses could be made available to all Veterans, at no cost to users.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Cohort A - cCBT-SP Program

Inclusion criteria

  • Veterans between the ages of 18 and 65
  • Currently living in Colorado, New York, Montana, Texas, or Utah who have accessed VA Care
  • Recent suicidal ideation (past month; C-SSRS Screener -Yes to Item 2) and history of lifetime suicidal behavior (lifetime, C-SSRS Screener - Yes to Item 6)
  • Reliable access to a computer/tablet and the internet
  • Ability to provide informed consent

Exclusion criteria

  • Active alcohol or substance use disorder, excluding Cannabis dependence, as determined by screening or electronic medical record
  • Identification of active psychosis or bipolar disorder, as determined via screening or electronic medical record
  • Severe cognitive impairment, as determined by screening or electronic medical record
  • Currently enrolled in/participating in another mental health-related intervention research study

Cohort B - cCBT-D Program

Inclusion criteria

  • Veterans between the ages of 18 and 65
  • Currently living in Colorado, New York, Montana, Texas, or Utah who have accessed VA care
  • Mild to moderate depressive symptoms, as determined by the PHQ-9, (score of 5-14)
  • Reliable access to a computer/tablet and the internet
  • Ability to provide informed consent

Exclusion criteria

  • PHQ-9 score below 4 or 15 and above
  • Active alcohol or substance use disorder, excluding Cannabis dependence, as determined by screening or electronic medical record
  • Identification of active psychosis or bipolar disorder, as determined via screening or electronic medical record
  • Severe cognitive impairment, as determined by screening or electronic medical record
  • Currently enrolled in/participating in other intervention research study

Treatment and study plan

c-CBT for Suicide Prevention

Behavioral

Online c-CBT for SP The computerized Cognitive Behavioral Therapy for Suicide Prevention (cCBT-SP) course is comprised of 12 online sessions and is augmented by use of a companion workbook.

c-CBT or Depression

Behavioral

The computerized Cognitive Behavioral Therapy for Depression (cCBT-D) course is comprised of 12 online sessions and is augmented by use of a companion workbook.

Primary outcomes

  1. Client Satisfaction Questionnaire

    Time frame: 12 weeks

    Acceptability

  2. Internet Evaluation and Utility Questionnaire

    Time frame: 12 weeks

    Acceptability

  3. Internet Impact and Effectiveness Questionnaire

    Time frame: 12 weeks

    Acceptability

  4. Narrative Evaluation of Intervention Interview

    Time frame: 12 weeks

    Acceptability

  5. Recruitment Rate

    Time frame: 12 weeks

    Number of individuals who consented to participate

  6. Completion of intervention

    Time frame: 12 weeks

    Number of participants who completed most or all of the sessions

Secondary outcomes

  1. Beck Scale for Suicide Ideation

    Time frame: 12 weeks

    Change in suicidal ideation

  2. Patient Health Questionnaire-9

    Time frame: 12 weeks

    Change in depression symptoms

  3. Posttraumatic Stress Disorder Checklist-5

    Time frame: 12 weeks

    Change in PTSD symptoms

  4. Generalized Anxiety Disorder-7

    Time frame: 12 weeks

    Change in anxiety symptoms

  5. Computerized Adaptive Testing - Suicide Scale

    Time frame: 12 weeks

    Change in suicidal ideation

Study contacts

Contact information is provided by the study sponsor or research team.

Kelly A Stearns-Yoder, MA

CONTACT

[email protected]

720-723-6477

Sponsors and collaborators

Lead sponsor

VA Eastern Colorado Health Care System

Fed

Registry information

Official study title

Implementing Computerized Cognitive Behavioral Therapies for Suicide Prevention and Depression Among At-Risk Rural and Urban Veterans

Important dates

Study start
2024
Primary completion
2026
Study completion
2026
First posted
Apr 19, 2024
Registry last updated
Feb 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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