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OpenTrials
Completed

NCT Number: NCT02147847

Computer-Based Auditory Rehabilitation

Hearing in noisy environments is a perceptual problem that is ubiquitous in modern industrialized societies. This particular listening context offers a particular challenge to individuals living with hearing impairment (30 million in US alone) even after treatment with hearing aids or cochlear implants. The ability of the brain to extract regularities from the environment and suppress distracting information can be improved with intensive cognitive training. The investigators will test whether the hearing in noise abilities of adults living with hearing impairment can be improved with a cognitive training paradigm.

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Key information

Age range

50 year–85 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Massachusetts Eye and Ear Infirmary, Boston, Massachusetts, United States

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About this study

Hearing impairment (HI) represents the most common cause of moderate to severe disability in the world, with an estimated prevalence of 636 million individuals (30 million in the US alone). Amplification devices (i.e., hearing aids) are commonly used to compensate for HI stemming from acoustic trauma, ototoxic insult, normal aging or other sources of cochlear degeneration. The chief complaint of individuals with HI is hearing in the types of noisy environments that characterize most work, educational, and social situations. Unfortunately, hearing aids do not completely address the perceptual impairments in these situations. That is because the difficulties that individuals with HI have hearing in noise result from the reduced salience of cues that are used to sort out auditory scenes. Making sounds louder improves audibility, but does not afford adaptation of the brain to the abnormal coding of sensory information by the damaged cochlea. The investigators will test whether the hearing in noise abilities of adults living with hearing impairment can be improved with a cognitive training paradigm.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Binaural sensorineural hearing impairment
  • Use of binaural hearing aids
  • Native English Speaker

Exclusion criteria

  • Significant cognitive impairment
  • Significant motor impairment
  • History of neurological disease/head trauma
  • Use of psychotropic and thyroid medications

Treatment and study plan

Video game based training 1

Behavioral

32 one-hour, home-based training sessions over 8 weeks

Video game based training 2

Behavioral

32 one-hour, home-based training sessions over 8 weeks

Primary outcomes

  1. Speech Perception in Noise

    Time frame: up to 3 months

    Participants will report words spoken by a target speaker while several speakers serve as distractors.

Secondary outcomes

  1. Frequency Modulation Detection

    Time frame: up to 3 months

    We will measure the detectability of frequency excursions psychoacoustically.

  2. Stroop Task

    Time frame: up to 3 months

    Participants will be asked to attend and report one feature of a stimulus while ignoring another

  3. Letter-Numbers Sequencing Test

    Time frame: up to 3 months

    Participants are asked to repeat a string of letters and numbers.

Sponsors and collaborators

Lead sponsor

Massachusetts Eye and Ear Infirmary

Other

Registry information

Official study title

Neurological Treatment to Improve the Hearing in Noise Abilities of Older Adults With Hearing Impairments.

Important dates

Study start
2015
Primary completion
2016
Study completion
2016
First posted
May 28, 2014
Registry last updated
Oct 18, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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