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Completed

NCT Number: NCT02399293

Computer-based Attention Training in Patients With Acquired Brain Injury

Investigates computer based cognitive rehabilitation and training using the N-back task with a Visual Search task as an active control. The overall purpose is to provide (further) evidence about the efficacy (or lack of efficacy) of the N-back task and to find points of convergence and divergence between patients with acquired brain injury and non-impaired subjects.

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Key information

Conditions

Brain Injuries Brain Diseases Central Nervous System Diseases Craniocerebral Trauma Nervous System Diseases Trauma, Nervous System Wounds and Injuries

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • subjects should be able to do both task at level at the time of recruitment
  • Informed consent
  • (for brain injured patients) training must not interfere with treatment as usual.
  • (for brain injured patients) no symptoms which hinder testing and training. I.e. aphasia, deafness, tetraplegia etc.

Treatment and study plan

N-back

Behavioral

The N-back task required patients to monitor a continuous sequence of stimuli (in this experiment audio and visual stimuli). Press a button if the current stimulus is the same as that shown N back in the sequence. N increases if performance is good and decreases if performance is poor.

Subjects train for 20 days, 12 blocks a day, 20+N trials per block. That is 240 blocks in total. A minimum of 10 blocks per day counts as a successfully trained day.

Visual Search

Behavioral

The Visual Search task consists of a NxN array of shapes. Press the button if a certain target stimulus is present in this array. N increases if performance is good and decreases if performance is poor.

Subjects train for 20 days, 12 blocks a day, 20+N trials per block. That is 240 blocks in total. A minimum of 10 blocks per day counts as a successfully trained day.

Primary outcomes

  1. Change from baseline Raven's advanced progressive matrices at the end of training

    Time frame: within five days after 20 full training days has been completed. Expected 3-6 weeks after baseline.

Secondary outcomes

  1. Change from baseline WAIS-III Working Memory Index at the end of training

    Time frame: within five days after 20 full training days has been completed. Expected 3-6 weeks after baseline.

  2. Change from baseline WAIS-III Processing Speed Index at the end of training

    Time frame: within five days after 20 full training days has been completed. Expected 3-6 weeks after baseline.

  3. Change from baseline Operation Span at the end of training

    Time frame: within five days after 20 full training days has been completed. Expected 3-6 weeks after baseline.

  4. Change from baseline Stroop color-text interference at the end of training

    Time frame: within five days after 20 full training days has been completed. Expected 3-6 weeks after baseline.

  5. Change from baseline AMPS at the end of training

    Time frame: within five days after 20 full training days has been completed. Expected 3-6 weeks after baseline.

Sponsors and collaborators

Lead sponsor

University of Aarhus

Other

Collaborators

  • Regionshospitalet Hammel Neurocenter

Registry information

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Mar 26, 2015
Registry last updated
Mar 26, 2015

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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