Compression Stockings for Prevention of Hemodialysis Muscle Cramps

the Objectives of this clinical trial is :

1. examine the effect of using elastic compression stockings in the prevention of muscle cramps among hemodialysis patients. 2. Find out the difference between the effect of compression stockings in the prevention of muscle cramps with patients' sociodemographic and clinical data.

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Key information

Conditions

Muscle Cramp Muscular Diseases Musculoskeletal Diseases Nervous System Diseases Neurologic Manifestations Neuromuscular Manifestations Pathological Conditions, Signs and Symptoms Signs and Symptoms

Age range

18 year–70 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Imam AL-Hassan AL-Mujtaba Teaching Hospital, Karbala, Karbala Governorate, Iraq

About this study

Intradialytic muscles cramps are frequent complication, and common cause of early hemodialysis (HD) termination. These cramps are thought to be precipitated by intradialytic venous stasis and reduced tissue perfusion. Elastic compression stockings (ECS), compress the calf and thigh to counteract venous pooling, and increase venous return.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Those who are at least eighteen years old.
Both genders (male & female).
Patients who are conscious and cooperative.
Patients experiencing muscle cramps during previous hemodialysis session.
Patients who would like to participate in part in the study .
Patients with verbally communicated skills.

Treatment and study plan

compression stockings

Device

Patients in the Compression stockings group firmly wrapped compression stockings around their calves for 30 minutes, starting at the end of the second hour and continuing until the beginning of the third hour of the hemodialysis session. This was performed once per day for a single hemodialysis session.

Primary outcomes

Cramp Questionnaire Chart

Time frame: Baseline (pre-hemodialysis) and immediately post-hemodialysis, within a single session

The instrument was developed by Morris (2014), and permission was obtained from the author. It was used in the study to assess patients' muscle cramps. This scale is composed of five features of muscle cramps: frequency, duration, pain level, leg temperature, and discomfort. These features are comprehensively scored as a level of muscle cramps ranging from 0 to 13.
Visual analogue scale (VAS) for pain

Time frame: Baseline (pre-hemodialysis) and immediately post-hemodialysis, within a single session

The Visual Analogue Scale (VAS) is a validated, subjective scale for acute and chronic pain. It was initially introduced by Hayes and Patterson in 1921. Scoring involved self-reported symptom scales that are scored with a single handwritten mark placed at a single point along a 10 cm line representing continuity between the two ends of the scale - "no pain" at the left end (0 cm) of the scale and "worst pain" at the right end of the scale (10 cm).

Sponsors and collaborators

Lead sponsor

Karbala University

Other

Registry information

Official study title

The Role of Using Elastic Compression Stockings in the Prevention of Muscles Cramps Episode in Patients Undergoing Hemodialysis: A Randomized Controlled Trial

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2026
First posted: Dec 19, 2025
Registry last updated: May 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed