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NCT Number: NCT07033871

Comprehensive Geriatric Assessment in Chronic Disease Management for Older Adults in China: A Registry Study (CGACDM - Older Adults in China)

With the continuous development of China's economy and the improvement of medical standards, the life expectancy of the Chinese population has significantly increased. Against the backdrop of accelerating aging in China, the incidence of age-related chronic non-communicable diseases (NCDs), such as cardiovascular and cerebrovascular diseases and chronic respiratory diseases, has risen remarkably. These diseases are characterized by multiple comorbidities, high disability rates, and high mortality rates, severely compromising the quality of life of older adults, exacerbating family burdens, and straining healthcare systems. This constitutes one of the major challenges faced by aging societies. Therefore, early detection and intervention of chronic diseases in older adults are critical measures to address population aging.

Comprehensive geriatric assessment (CGA), a core specialty of geriatric medicine, serves as a fundamental framework for the clinical identification of geriatric syndromes and multidisciplinary management. It is emerging as a key pathway to promote "healthy aging." Guided by this premise, this study aims to explore the application value of CGA in managing chronic diseases among older adults, with the goal of achieving full-cycle management for early detection, diagnosis, and treatment of chronic conditions in China's elderly population.

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Key information

Age range

60 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 1. Aged 60 years or older 2. Diagnosed with chronic diseases in the circulatory, respiratory, digestive, nervous, or endocrine systems, consistent with corresponding disease diagnostic criteria; 3. Availability of complete medical records; 4. Clear consciousness and ability to independently answer questions; 5. Signed informed consent form.

Exclusion criteria

  • 1. Presence of any condition/circumstance which in the opinion of the investigator could significantly limit the complete follow up of the patient (e.g. tourist, non-native speaker or does not understand the local language, psychiatric disturbances).
  • Presence of serious/severe co-morbidities in the opinion of the investigator which may limit short term (i.e. 6 month) life expectancy.
  • Current participation in a randomised interventional clinical trial.

Treatment and study plan

comprehensive geriatric assessment

Diagnostic Test

The comprehensive geriatric assessment (CGA) is a multi dimensional diagnostic process used to determine the medi cal, psychological, and functional capabilities of a frail elderly person to develop a coordinated and integrated plan for treat ment and long-term follow-up.

Primary outcomes

  1. Major adverse events (MAE)

    Time frame: These data is collected during follow-up visit at 3/6/12/24/36 months after discharge

    Major adverse events (MAE) in overall population, defined as composite of all-cause death, Heart Failure hospitalization, recurrent myocardial infarction, stroke, etc.

Other outcomes

  1. Age for each participant

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  2. Gender for each participant

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  3. Height for each participant

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  4. Weight for each participant

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  5. Contact information for each participant

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  6. Past Medical History including disease history, surgical history, and family medical history

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  7. Lifestyle including smoking history and drinking, specify how many years smoking or drinking lasted and detail quantity per day

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  8. blood biochemical index:blood lipid

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  9. blood biochemical index:blood glucose

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  10. blood biochemical index:uric acid

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  11. blood biochemical index:urea

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  12. blood biochemical index:creatinine

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  13. blood biochemical index:C reactive protein

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  14. blood biochemical index:D-dimer

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  15. blood biochemical index:NT-proBNP

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

  16. Cardiac ultrasound

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

    The whole results of echocardiography report will be recorded. The indicates which can reflect cardiac function including Left ventricular ejection fraction, left ventricular end diastolic diameter, E/A ratio of bicuspid valve will be used to calculate the association with metabolites.

  17. Drug treatment

    Time frame: These data is collected from the cases' medical record in an average of 1 month after the sample recruiting

    Oral drug therapy, including antiplatelet drugs, antihypertensive drugs, lipid-lowering drugs, etc.

  18. Comprehensive Geriatric Assessment: Frailty

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  19. Comprehensive Geriatric Assessment: Sarcopenia

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  20. Comprehensive Geriatric Assessment: Falls

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  21. Comprehensive Geriatric Assessment: Disability

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  22. Comprehensive Geriatric Assessment: Dysphagia

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  23. Comprehensive Geriatric Assessment: Malnutrition

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  24. Comprehensive Geriatric Assessment: Urinary incontinence

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  25. Comprehensive Geriatric Assessment: Fecal incontinence

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  26. Comprehensive Geriatric Assessment: Constipation

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  27. Comprehensive Geriatric Assessment: Cognitive impairment

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  28. Comprehensive Geriatric Assessment: Anxiety state

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  29. Comprehensive Geriatric Assessment: Depressive state

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  30. Comprehensive Geriatric Assessment: Sleep disorders

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  31. Comprehensive Geriatric Assessment: Pain

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  32. Comprehensive Geriatric Assessment: Social support

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

  33. Comprehensive Geriatric Assessment: Home environment

    Time frame: These data were collected from the comprehensive geriatric assessment process within an average of 1 week after sample recruitment

Study contacts

Contact information is provided by the study sponsor or research team.

Yang Xinying Yang Xinying

CONTACT

[email protected]

0371-87160164

Sponsors and collaborators

Lead sponsor

Henan Provincial People's Hospital

Other

Collaborators

  • Beijing Institute of Heart, Lung and Blood Vessel Diseases
  • Geriatrics Research Institute of Henan Provincial People's Hospital

Registry information

Acronym: CGACDM - Older

Important dates

Study start
2025
Primary completion
2030
Study completion
2030
First posted
Jun 24, 2025
Registry last updated
Jun 24, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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