Comprehensive Biomarker ProfiliNg in PatieNts With VEntriCular TachyCardia, PremAtuRe VEntricular Contractions, and AVNRT

To systematically evaluate multiple biomarkers in patients ventricular tachycardia (VT), premature ventricular contractions (PVC), atrioventricular nodal reentrant tachycardia (AVNRT) undergoing catheter ablation to elucidate their mechanistic relevance and predictive value.

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Key information

Conditions

Arrhythmia Arrhythmias, Cardiac Cardiovascular Diseases Heart Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age ≥ 18 years
Catheter ablation due to VT, PVC, or AVNRT
Written informed consent

Exclusion criteria

Infection or inflammatory disease at time of sampling
Pregnancy
Inability to comply with study procedures
Life expectancy < 1 year not due to arrhythmia

Treatment and study plan

Primary outcomes

Association between baseline biomarker profiles and arrhythmia subtype (VT, PVC, AVNRT).

Time frame: 24 months

Sponsors and collaborators

Lead sponsor

University of Luebeck

Other

Registry information

Official study title

Comprehensive Biomarker ProfiliNg in PatieNts With VEntriCular TachyCardia, PremAtuRe VEntricular Contractions, and AVNRT (CONNECT-CARE)

Acronym: CONNECT-CARE

Important dates

Study start: 2026
Primary completion: 2030
Study completion: 2030
First posted: Feb 5, 2026
Registry last updated: Feb 5, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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