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Completed

NCT Number: NCT06032871

Comparisons of Two Airway Clearance Techniques

The goal of this clinical trial is to compare the effectiveness of two airway clearance techniques for patients with ventilator associated pneumonia. The main questions it aim to answer are:

* effect of the therapies on volume changes * outcome on sputum clearance Participants will receive airway clearance techniques of * chest physiotherapy * high frequency chest wall oscillation.

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Key information

Conditions

Airway Clearance Impairment Cross Infection Disease Attributes Healthcare-Associated Pneumonia Iatrogenic Disease Infections Lung Diseases Pathologic Processes Pathological Conditions, Signs and Symptoms Pneumonia Pneumonia, Ventilator-Associated Respiratory Tract Diseases Respiratory Tract Infections

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Chang Gung Memorial Hospital, Taoyuan, Taiwan

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About this study

Sputum can be accumulated in the airways of intubated patients, resulting in recurrent pneumonia. The airway clearance therapy is often utilized with chest physiotherapy or high frequency chest wall oscillation which has become popular for its easy of use and less time consuming to the healthcare workers. The main questions it aim to answer are on effectiveness of the therapies on lung volume changes and sputum clearance by two airway clearance techniques. With the oscillation of entire chest wall, the investigators hypothesize that the high frequency chest wall oscillation is more effectively clear sputum in the distal airways.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Diagnosed with chronic pulmonary disease
  • Diagnosed with ventilator associated pneumonia
  • Receive airway clearance therapy

Exclusion criteria

  • Head injury, spinal injury
  • Instable hemodynamics
  • Intercranial pressure > 20 cmH2O
  • Active hemoptysis
  • Empyema
  • Eye surgery
  • Abdominal distension
  • Chest tube insertion
  • Active tuberculosis

Treatment and study plan

high frequency chest wall oscillation

Procedure

Patients receive airway clearance by high frequency chest wall oscillation for 30 minutes twice a day.

Chest physiotherapy

Procedure

Participants received chest physiotherapy twice a day

Primary outcomes

  1. end-expiratory lung impedance

    Time frame: Measurement before intervention, 30 after, 1 hour and 2 hours after intervention

    Changes of global of impedance of lungs measure by the electrical impedance tomography

Secondary outcomes

  1. Weight of secretions

    Time frame: Sputum is collected before intervention, 30 after, 1 hour and 2 hours after intervention

    Sputum amount is weighted.

Sponsors and collaborators

Lead sponsor

Hui-Ling Lin

Other

Registry information

Official study title

Comparison of Two Airway Clearance Techniques by Electrical Impedance Tomography- a Parallel Study

Important dates

Study start
2023
Primary completion
2023
Study completion
2023
First posted
Sep 13, 2023
Registry last updated
Sep 19, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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