LifePort® perfusion device
DeviceRenal Perfusion with LifePort® perfusion device
Other names: A
NCT Number: NCT02826213
Comparison of two techniques of renal pre-transplant infusion on the evolution of renal function in the recipient: multicentre randomized trial
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Notify Me50 year and older
All sexes
Observational
Coordination Hospitalière de PMO , Pôle USSAR-Anestéthésie -Réa CHU-ANGERS, Angers, France
Both machines differ in their operation: the LifePort® machine manufactured by the "Organ Recovery System (ORS)," says renal perfusion by maintaining a continuous perfusion pressure that is adjustable, while the Waves machine company "Medical Waters" assures infusion maintaining a controlled pulsatile flow.
Both machines are now available but the investigators currently have no study of whether an infusion type is superior to the other in terms of results on renal function recipients.
Study the impact of both types of infusion on renal function recipients evaluated in the early days of transplantation, at three months and one year after the transplant.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
RENAL Donors:
Inclusion criteria
Exclusion criteria
RENAL recipients:
The grafts are addressed to transplant centers in France according to the distribution rules of the National Center of Distribution of transplants . (Pôle National de Répartition des Greffons (PNRG).
Renal Perfusion with LifePort® perfusion device
Other names: A
Renal Perfusion with Waves perfusion device
Other names: B
Time frame: 3 months
Rate of patients with a Glomerular Filtration Rate (GFR) calculated by the MDRD ≥ 45 ml / min / 1,73m² (considered normal in a renal graft) at 3 months post-transplantation (MDRD: Modification of Diet in Renal the Disease)
Time frame: 1 week
Time for obtaining a serum creatinine <250 mg / dL and need for dialysis in recovery during the first seven days post transplant.
Time frame: 1 month
Absence of a recovery renal function at 1 month.
Time frame: 1 year
Modification of Diet in Renal the Disease at 1 year
Time frame: 1 year
graft survival rate at 1 year.
Time frame: 3 months
Results of analyzes of kidney biopsies punctures to 3 months.
University Hospital, Tours
Other
Comparison of Two Techniques of Renal Pre-transplant Infusion on the Evolution of Renal Function in the Recipient: Multicentre Randomized Trial
Acronym: RENOMAP
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