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NCT Number: NCT06610955

Comparison of Two Different Intensity Exercises on Young Women With Obesity

Obesity is one of the most common preventable public health problems. Diet regulation and exercise practices are the most commonly used methods in reducing fat tissue. There are various exercise methods applied in the weight loss process and the effects of different types of exercise modalities on body fat rate and metabolic status.The aim of our study is to determine the effects of high intensity interval exercise and moderate intensity continuous exercise on serum , omentin, leptin and adiponectin levels, anthropometric measurements used in obesity follow up, body fat percentage and their effects on the quality of sleep and life of women with obesity.

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Key information

Age range

18 year–45 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Kırşehir Ahi Evran Üniversitesi

Kırşehir, 40100, Turkey (Türkiye)

Location status: Recruiting

Location contact

Figen Tuncay, Prof.Dr.

CONTACT

[email protected]

5353046401 ext. +90

About this study

Female participants aged 18-45 with a body mass index of 30-40 kg/m² who met the inclusion and exclusion criteria were randomized into two groups using a simple randomization method using a computer. One group will perform high intensity interval exercise with an Ergoline bicycle ergometry device for 45 minutes a day, 5 days a week for 8 weeks, while the other group will perform moderate intensity continuous exercise on the same device. Peripheral venous blood samples will be taken from all participants at the beginning and end of the study, anthropometric measurements used in obesity monitoring of all participants will be taken and noted, and participants will be asked to fill out questionnaires containing questions about their sleep and quality of life. The analysis of the blood samples taken will be carried out in the Biochemistry Laboratory of Kırşehir Ahi Evran University. The data of our study will be analyzed with the statistical package program SPSS version 23.0.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Female between the age of 18-45
  • BMI 30-40 kg/m²
  • Primary obesity

Exclusion criteria

  • Patients with cardiac, pulmonary, endocrinological, rheumatological diseases
  • Pregnancy and breastfeeding
  • Using antipsychotics, antidepressants (lithium, tricyclic antidepressants, mono amino oxidase inhibitors), anticonvulsants, antihistamines, glucocorticoids, antidiabetics (sulfonylureas, insulins, glitazones) sex hormones
  • Using oral contraceptives
  • History of bariatric surgery
  • Patients using obesity medication in the last 6 months, complying with a regular diet and exercise program
  • Presence of orthopedic or neurological problems that difficulty of participate aerobic exercise training

Treatment and study plan

High Intensity Interval Training

Other

After a 10 minutes warm up exercise, participants will exercise with a bicycle ergometry device at 80% of their maximum heart rate for 4 minutes, and the active recovery period will be 3 minutes (4x4 minutes). During the recovery period, the participant will exercise with the Ergoline bicycle ergometry system for 4 sets at 60% of their maximum heart rate for 3 minutes. A total of 45 minutes exercise session will be completed with a 10 minutes cool down exercise. Exercise will be done 5 days a week for a total of 8 weeks. In the first 4 weeks, exercise will be done at 80% intensity, and in the following weeks, the exercise intensity will be increased by 5% each week, respectively, to 85%, 90%, 95%, and 100% in the last week.

Moderate Intensity Continuous Training

Other

Following a 10 minutes warm up exercise, participants will exercise continuously for 30 minutes at 65% of their maximum heart rate with the Ergoline bicycle ergometry system. A 5 minutes cool down exercise will end the 45 minutes exercise session. The exercise duration is 5 days a week for a total of 8 weeks.

Primary outcomes

  1. Serum adipokine levels

    Time frame: 8 weeks

    This study aimed to investigate the effects of high intensity interval exercise and moderate intensity continuous exercise on serum adiponectin, leptin and omentin levels in young women with obesity.

Secondary outcomes

  1. Anthropometric measurement

    Time frame: 8 weeks

    waist and hip circumference measurements

  2. Percentage of body fat

    Time frame: 8 weeks

    skinfold thickness will measure with skinfold caliper

  3. The impact of weight on quality of life

    Time frame: 8 weeks

    The impact of weight on quality of life will describe with The Impact of Weight on Quality of Life-Lite index

  4. Quality of sleep

    Time frame: 8 weeks

    Sleep quality will describe Pittsburgh sleep quality index

Study contacts

Contact information is provided by the study sponsor or research team.

Elif Kapaklı, RA

CONTACT

[email protected]

5432139966 ext. +90

Figen Tuncay, Professor

CONTACT

[email protected]

5353046401 ext. +90

Sponsors and collaborators

Lead sponsor

Ahi Evran University Education and Research Hospital

Other

Collaborators

  • Kirsehir Ahi Evran Universitesi

Registry information

Official study title

Effects of High Intensity Interval Training vs. Moderate Intensity Continuous Training on Fat Loss,Serum Adiponectin,Leptin,Omentin Level,Sleep and Quality of Life in Young Females With Obesity

Important dates

Study start
2024
Primary completion
2025
Study completion
2025
First posted
Sep 24, 2024
Registry last updated
Feb 5, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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