Skip to main content
OpenTrials
Not Yet Recruiting

NCT Number: NCT07548749

Comparison of Transphyseal Screws and Eight Plates in Hemiepiphysiodesis for Coronal Knee Deformities: Short-Term Results

Coronal angular deformities of the lower limbs, such as bow legs and knock-knees, are frequently observed in childhood. While many cases are considered normal and resolve on their own, when these deformities become significant and progressive, they can disrupt the quality of life, leading to gait disturbances, pain, and in severe instances, joint instability. Additionally, these deformities may have indirect effects on other joints like the hip and ankle, and most importantly, they increase the risk of early osteoarthritis in the knee .

It is generally accepted that a significant deformity that persists up to preadolescence will not correct spontaneously. Physiological alignment of the lower limb is crucial for the symmetrical distribution of weight over the surfaces of the joints, especially the knee. Indeed, severe coronal malalignment has been linked to knee pain, altered gait, and occasionally patellofemoral problems .

Not Yet Recruiting

Trial opening soon.

Get Notified

Key information

Age range

3 year–14 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Both gender (males and females)
  • Children ≥3 years old and growing children 2 years at least remaining in growth ( skeletal immature)
  • Cases with progressive knee deformities around knee at any side.

Exclusion criteria

  • 1. Physeal closure.
  • Physiological deformity in younger ages that could be managed conservatively ( age < 3 years )
  • Cases with metabolic or chronic illness conditions unresolved.

Treatment and study plan

hemiepiphysiodesis

Procedure

Hemiepiphysiodesis is a safe, effective, and minimally invasive method for correcting angular deformities in growing children. The two main techniques-transphyseal screw and eight-plate-both rely on guided growth principles but differ in mechanics, control, and risk profile. Careful patient selection, timing, and follow-up are key to achieving optimal results.

Primary outcomes

  1. correction of deformity

    Time frame: 6 months after surgery

Study contacts

Contact information is provided by the study sponsor or research team.

Hossam Hosny omar Mansour

CONTACT

[email protected]

+201032366753

Sponsors and collaborators

Lead sponsor

Sohag University

Other

Registry information

Official study title

Management of Coronal Deformities Around the Knee With Hemiepiphysiodesis Using Transphyseal Screws Versus Eight Plates , Short Term Results

Important dates

Study start
2026
Primary completion
2026
Study completion
2027
First posted
Apr 23, 2026
Registry last updated
Apr 23, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.