Comparison of the Effects of External Oblique Intercostal Plane Block, Subcostal Transverse Abdominis Plane Block, and Their Combination in the Management of Postoperative Pain in Laparoscopic Cholecystectomy Surgery

This study aims to compare the efficacy of Subcostal Transversus Abdominis Plan Block, External Oblique Intercostal Plan Block and the combination of these two blocks, which are used in anesthesiology practice for postoperative pain in laparoscopy cholecystectomy surgery.

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Key information

Conditions

External Oblique Intercostal Plane Block Subcostal Transverse Abdominis Plane Block

Age range

18 year–80 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patients scheduled for laparoscopic cholecystectomy surgery
Patients aged between 18 to 80 years
Having an anesthesiology risk assessment of ASA I, II, or III

Exclusion criteria

Patients who do not give written and oral consent
Patients with coagulopathy
History of allergic reaction or intoxication by local anesthetics
Severe organ failure
Mental retardation or illiteracy
Presence of infection on the injection site
Pregnancy
Patients whom the procedure is extended to open cholecystectomy

Treatment and study plan

Subcostal Transversus Abdominis Plane Block

Procedure

Under ultrasound guidance, 30 ml of bupivacaine is injected along the fascia of transversus abdominis muscle.

External Oblique Intercostal Plane Block

Procedure

Under ultrasound guidance, 30 ml of bupivacaine is injected between the fascias of external oblique and intercostal muscles.

external oblique intercostal plane block and subcostal transversus abdominis plane block combination

Procedure

The combination of the two blocks will be applied in 15 ml of volume for each.

Primary outcomes

Postoperative Analgesic Consumption

Time frame: 24 hours postoperatively

The opioid consumption via patient controlled analgesia (PCA) in 24 hours postoperatively

Secondary outcomes

Postoperative Pain Scores

Time frame: up to 24 hours after surgery

Postoperative pain will be assessed using Numeric Rating Scale (NRS) at 30 mins, and 1, 4, 8, 12, 24 hours after surgery.

Study contacts

Contact information is provided by the study sponsor or research team.

Faruk Kömez

CONTACT

[email protected]

+90 507 688 28 50

Sponsors and collaborators

Lead sponsor

Istanbul Medeniyet University

Other

Registry information

Important dates

Study start: 2025
Primary completion: 2025
Study completion: 2025
First posted: Sep 18, 2025
Registry last updated: Sep 18, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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