NCT Number: NCT07435688
The goal of this clinical trial is to compare the effectiveness of conventional mirror therapy and robotic mirror mode training in promoting upper extremity motor recovery in adult patients with ischemic stroke during the early subacute phase. The main questions it aims to answer are:
Does mirror mode of a robotic hand device result in greater motor function recovery compared to conventional mirror therapy?
Are there differences between the groups in somatosensory improvement and gross motor skill outcomes?
Do both intervention modalities result in clinically significant improvements in motor and functional outcomes?
Researchers will compare a conventional mirror therapy group and a robotic-assisted mirror mode group to determine which provides more significant gains in motor function, somatosensory input, and functional use of the paretic arm.
Participants will:
Receive standard physiotherapy sessions for 6 weeks
Be randomly assigned to either mirror therapy or robotic mirror mode intervention
Be evaluated using Fugl-Meyer Assessment, ARAT, Box and Block Test, Wolf Motor Function Test and Tactile/proprioceptive sensory test using Fugl-Meyer Assessment Sensory subsection.
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Notify Me18 year and older
All sexes
Interventional
Not applicable
Istanbul University- Cerrahpasa, Istanbul, Büyükcekmece, Turkey (Türkiye)
Upper extremity motor impairment is one of the leading causes of functional disability following stroke. Although conventional therapies promote some degree of recovery, restoring hand function remains a major challenge, particularly in patients with severe paresis. Mirror therapy has been widely used due to its affordability and portability. However, proprioceptive feedback limitations and the potential mismatch between visual and somatosensory input reduce its effectiveness.
This study investigates an innovative approach that combines visual illusion and proprioceptive input using a robotic hand device in mirror mode. The robotic intervention is designed to synchronize joint motion with visual feedback, potentially enhancing the mirror neuron system's activation and promoting neuroplastic changes more efficiently than conventional mirror therapy.
The study will be conducted over a 6-week period with stroke patients in the early subacute phase. Both groups will receive equivalent durations of upper limb training in addition to conventional physiotherapy.
This trial aims not only to compare motor outcomes but also to evaluate whether motor improvements translate into functional hand use and to explore differences in somatosensory gains between interventions. By addressing both visual and proprioceptive components of motor learning, this research may guide future clinical strategies for individualized stroke rehabilitation.
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Mirror mode of the hand robot group will mimic the movement of the unaffected arm. The robot will provide proprioceptive and visual feedback and make patient believe that the affected arm is moving.
Other names: Syrebo C12 / SY-HRC12
Patients in the mirror therapy group will glance at the reflection of their non-affected arm and fall into the illusion that their non-affected limb is moving. This is supposed to assist patients regain motor deficits by reducing non-use paralysis.
Time frame: 30 minutes
The Fugl-Meyer Assessment-Upper Extremity is a stroke-specific, performance-based impairment scale and gold-standard measure of post-stroke motor recovery that quantifies upper limb motor function using a standardized ordinal scoring system assessing reflex activity, movement control, coordination, and joint function.
Time frame: 15 minutes
The Action Research Arm Test (ARAT) is a performance-based assessment designed to evaluate upper limb function by measuring the ability to grasp, grip, pinch, and perform gross motor movements. It is particularly sensitive to changes in hand and arm function after stroke and is frequently used in both clinical and research settings to monitor motor recovery.
Time frame: 30 minutes
The Wolf Motor Function Test (WMFT) is a widely used, time-based assessment that evaluates upper extremity motor ability through a series of functional and strength-related tasks in individuals with stroke. It measures both the time taken to complete 15 standardized activities and the quality of movement, providing objective data on motor recovery.
Time frame: 5 minutes
The Box and Block Test is a standardized, performance-based measure of gross manual dexterity that quantifies upper extremity function by counting the number of blocks transferred within 60 seconds.
Zeynep Lide Uz
Other
Comparison of The Effectiveness Of Mirror Therapy And Mirror Mode of a Hand Robot in Upper Extremity Motor Recovery After Stroke
Acronym: mirror_robot
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