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OpenTrials
Completed

NCT Number: NCT07048834

Comparison of the Effectiveness of Articaine Local Infusion and Lidocaine Nerve Block in Lower Posterior Tooth Extraction.

In this study 60 adult patients will participate and divided into two groups (30 for each). The first group will be anesthetized using 2 % lidocaine with 1:80,000 adrenaline by inferior alveolar nerve block technique, while the second group will be anesthetized using 4 % articaine with 1:100,000 adrenaline via buccal and lingual infiltration technique in posterior teeth area. Then patients will wait for five minutes after receiving a local anesthetic injection before extraction could begin.

After that every tooth's buccal, lingual, mesial, and distal surfaces will be examined using a disposable dental explorer. Then by visual analog scale (VAS) which provides accessible, sensitive, valid, and reliable means to measure a variety of subjective parameters the pain score will be registered during tooth extraction.

Female patients who are breastfeeding or pregnant, those allergic to local anesthetics, lacking full mental ability, currently taking opioids, having an infection at the extraction site, or those under the influence of medicines that alter their perception of pain will be excluded from the study.

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Key information

Conditions

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

Ahl Al Bayt University

Karbala, Iraq

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • clinically healthy patients

Exclusion criteria

  • Breastfeeding or pregnant
  • Allergic to local anaesthetics drugs
  • Lack full mental ability
  • Infection at the extraction site
  • Patient who currently taking opioids or under the influence of medicines that alter their perception of pain are not candidates for tooth extraction

Treatment and study plan

lidocaine local anesthetic drug

Other

Lidocaine Nerve Block technique

articaine local anesthetic drug

Other

Articaine Local Infusion technique

Primary outcomes

  1. visual analog scale (VAS)

    Time frame: five minutes

    It usually is a horizontal line, 100 mm in length, anchored by word descriptors at each end, for example, that represent the severity of symptoms from 0 "no symptoms" to 10 "very severe symptoms." The patient marks on the line the point that the patient believes represents his or her perception of his or her current state.

Sponsors and collaborators

Lead sponsor

Amjed Fouad Hussein

Other

Registry information

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Jul 3, 2025
Registry last updated
Jul 9, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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