Comparison of the Clinical Performance of High Strength Hybrid Ceramic Indirect Restorations Cemented on Endodontically Treated Teeth Using Bioactive Versus Conventional Self Adhesive Resin Cements.

Cementation of indirect restoration is a determinant of the success or failure of the fabricated restoration and consequentially the entire tooth. While there are numerous commercially available resin cements in the dental market, not all have been sufficiently assessed with significant follow up periods to clinically determine their success or failure. As such, this research will be conducted to elucidate if there is a viability to the cementation of indirect hybrid ceramic blocks over endodontically treated teeth using bioactive self-adhesive resin cement and determining whether it provides a clinical advantage and improved restoration serviceability in the oral cavity.

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Key information

Conditions

Endodontically Treated Molar Dental Pulp Diseases Stomatognathic Diseases Tooth Diseases Tooth, Nonvital

Age range

21 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Patient Related Criteria:
Adult patients (age: 21-50 years) of both genders.
Able to tolerate necessary restorative procedures.
Willing to sign the informed consent.
Accepts the follow-up period.

Tooth Related Criteria:

Endodontically treated first and second permanent molars.
Access cavities with one missing proximal wall i.e. Occluso-mesial/distal cavities
Patients with proper oral hygiene

Exclusion criteria

Endodontically treated anterior, premolar and third molar teeth
Badly broken-down teeth
Hopelessly carious/destructed teeth necessitating extraction
Mobile teeth, indicating periodontal disease or trauma.
External or internal resorption.
Cervical carious lesions
Medically compromised patients
Patients with known allergies to Latex and/or resinous material

Treatment and study plan

Resin Cement

Other

Bioactive self adhesive resin cement (SHOFU BeautiLink) used to cement indirect restorations to endodontically treated molars.

Primary outcomes

Modified USPHS Criteria

Time frame: 2 years

Study contacts

Contact information is provided by the study sponsor or research team.

Ahmed N Shalaby, Masters Restorative Dentistry

CONTACT

[email protected]

+201014850792

Sponsors and collaborators

Lead sponsor

Cairo University

Other

Registry information

Official study title

Clinical Performance of CAD/CAM Hard Hybrid Ceramic Overlays on Endodontically Treated Molars Using Bioactive Versus Conventional Self-Adhesive Resin Cement: Two-Year Randomized Clinical Trial

Important dates

Study start: 2025
Primary completion: 2026
Study completion: 2027
First posted: Jan 22, 2025
Registry last updated: Jun 10, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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Completed