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OpenTrials
Completed

NCT Number: NCT00853437

Comparison of Techniques for Assessing Cardiac Output and Preload in Critically Ill Pediatric Patients

The ability to measure cardiac output (CO) accurately and reproducibly at frequent intervals remains elusive to the clinician caring for critically ill pediatric patients even though a large proportion of these children are known to have hemodynamic compromise as a result of their illness. Current techniques used in adults to measure CO are not suitable for routine use with pediatric patients. A new ultrasound dilution approach provides an opportunity to measure cardiac output and blood volumes in pediatric patients. The main aim of this study is to compare CO measured by the new method with the clinician's estimate and implied CO from the measurement of the arteriovenous oxygen content difference.

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Key information

Conditions

Cardiac Output

Age range

Up to 16 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Golisano Children's Hospital

Rochester, New York, 14642, United States

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with in situ central venous and arterial catheters
  • Ability to draw blood from arterial and central venous catheters
  • Presence of parent or guardian to provide consent

Exclusion criteria

  • Patients over 16 years of age.

Treatment and study plan

Primary outcomes

  1. Compare CO measured by the new method with clinician's estimate and implied CO from measurement of arteriovenous oxygen content difference.

    Time frame: 5-8 minutes minimum

Secondary outcomes

  1. Measure blood volumes to compare effects of volume infusion and furosemide.

    Time frame: 5-8 minutes minimum

Sponsors and collaborators

Lead sponsor

Transonic Systems Inc.

Industry

Collaborators

  • National Heart, Lung, and Blood Institute (NHLBI)

Registry information

Acronym: GCH

Important dates

Study start
2009
Primary completion
2011
Study completion
2011
First posted
Mar 2, 2009
Registry last updated
May 27, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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