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NCT Number: NCT05564455

Comparison of SRK-T With Kane Formula for Prediction of Refractive Outcome After Phacoemulsification

Cataract is a leading cause of blindness in the world. Cataract surgery is one of the most commonly performed ocular procedures. We aim to compare the newer generation biometry formula; the Kane formula with the commonly used SRK-T formula for intraocular power calculation in uneventful phacoemulsification surgery to assess the post-operative refractive outcomes at one month post-surgery.

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Key information

Conditions

Cataract; Surgery; Phacoemulsification; Biometry; Intraocular Lens Power Cataract Eye Diseases Lens Diseases

Age range

40 year–100 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Fauji Foundation Hospital

Rawalpindi, Punjab Province, Pakistan

About this study

Purpose: To compare post-operative refractive outcome with Sanders Retzlaff Kraff theoretical (SRK T) and Kane formulae for intraocular lens (IOL) power calculation in cataract patients Study Design: Prospective, interventional study Place and Duration of Study: Department of Ophthalmology, Fauji Foundation Hospital, Rawalpindi Material and Methods: A total of a 70 eyes, 35 in each group will be included in our study. The patients will be randomly divided into two groups. In cases of bilateral cataract, one eye will be included in each group for better control. IOL power calculation in Group A will be done with the SRK-T formula and in group 2 with the Kane Formula. Autokeratometry and A-scan ultrasound will be done for biometry. Inclusion criteria will be uncomplicated cataract in both genders. Exclusion criteria will be ocular trauma, uveitis, previous intraocular surgery, or any retinopathy. All patients will undergo phacoemulsification with foldable lens implantation by two experienced surgeons. Post-operative refractive outcome will be evaluated at one month after surgery. The two groups will be compared.

Results: The results will be calculated by SPSS. Conclusion: A conclusion will be drawn on the basis of our results.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Senile cataract (nuclear, cortical, posterior subcapsular, mature, hypermature cataract)
  • Absence of other ocular pathology causing diminished visual acuity
  • patients above 40 years of age
  • Astigmatism > 2.5 diopters

Exclusion criteria

  • Retinal diseases
  • Maculopathy
  • Uveitis
  • Complications during phacoemulsification
  • Combined procedures
  • Previous ocular surgery
  • Trauma
  • Secondary cataract

Treatment and study plan

Biometry with Kane formula

Other

Kane formulae for intraocular lens (IOL) power calculation in cataract patients

Biometry with SRK-T formula

Other

Sanders Retzlaff Kraff theoretical (SRK T) formulae for intraocular lens (IOL) power calculation in cataract patients

Primary outcomes

  1. Visual acuity (Snellen/logMAR) and refractive error (automated refraction in diopters)

    Time frame: 1 month post-operatively

    The visual acuity and refractive error of the patients will be measured 1 month post-operatively to compare between the two groups

  2. Spherical equivalent in diopters

    Time frame: 1 hour to 1 year

    The spherical equivalent of the patients will be measured 1 month post-operatively to compare between the two groups

  3. Post-operative refractive outcome in diopters

    Time frame: 1 hour to 1 year

    Post-operative refractive outcome will be compared with intended refractive outcome

Sponsors and collaborators

Lead sponsor

Foundation University Islamabad

Other

Registry information

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Oct 3, 2022
Registry last updated
Nov 2, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

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This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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