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OpenTrials
Completed

NCT Number: NCT02764827

Comparison of Skin Prick Testing Results of Local and Imported Pollen Allergen Extracts and Specific IgE

Pollen allergen extracts are prepared locally and checked for efficacy by comparison to imported allergens and specific IgE.

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Key information

Conditions

Immediate Type Hypersensitivity

Age range

18 year–60 year

Sex eligibility

All sexes

Study type

Observational

About this study

Skin prick test (SPT) and specific IgE (sIgE) are approved for evaluation of allergen sensitization. Local allergen extracts are cheaper and more available but need standardization. Pollen allergen extracts: Bermuda, Johnson and careless weed are locally prepared and compared mean wheal diameter of skin prick test to imported allergens and also to specific IgE.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Positive skin prick test to Bermuda or Johnson or careless weed

Exclusion criteria

  • Chronic diseases such as heart disease, liver, renal and severe sepsis
  • Severe allergic symptoms such as anaphylaxis
  • Extensive skin rashes
  • Pregnancy

Treatment and study plan

Pollen sensitization

Biological

Skin prick test with local and imported Bermuda, Johnson and careless weed allergen extracts at concentration of 10,000, 3,000, 1,000 and 300 AU/mL and measure specific IgE levels

Primary outcomes

  1. Mean wheal diameter of local and imported grass and weed pollens

    Time frame: 18 months

    compare mean wheal diameter of skin prick test of different concentration among local, imported allergen extract and specific IgE levels of Bermuda grass, Johnson grass and careless weed

  2. sIgE levels of Bermuda grass,Johnson grass and careless weed

    Time frame: 18 months

    Measure level of sIgE of Bermuda grass,Johnson grass and careless weed and compare to SPT results

Sponsors and collaborators

Lead sponsor

Mahidol University

Other

Registry information

Official study title

Comparison of Skin Prick Testing Results of Local and Imported Pollen Allergen Extracts (Bermuda ,Johnson Grasses and Careless Weed) With Specific IgE Levels.

Important dates

Study start
2014
Primary completion
2016
Study completion
2016
First posted
May 6, 2016
Registry last updated
May 10, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.