Islamabad Dental Hospital
Islamabad, Federal, 45720, Pakistan
NCT Number: NCT07458139
This randomized controlled clinical trial will compare external apical root resorption in patients undergoing maxillary canine retraction using modified corticotomy-assisted frictionless T-loop mechanics versus conventional frictionless T-loop mechanics. Sixty orthodontic patients requiring extraction of maxillary first premolars will be randomly assigned to two groups. Changes in canine root length will be measured on panoramic radiographs taken before and after retraction to determine the extent of external apical root resorption. The study will evaluate whether modified corticotomy-assisted retraction results in different root resorption outcomes compared to conventional retraction.
Trial opening soon.
Get Notified12 year–30 year
All sexes
Interventional
Not applicable
Islamabad, Federal, 45720, Pakistan
External apical root resorption is a known complication of orthodontic treatment and may be influenced by the magnitude and duration of orthodontic force. Methods that accelerate tooth movement may reduce overall treatment time and potentially influence the extent of root resorption.
Corticotomy-assisted orthodontics is based on the regional acceleratory phenomenon, which enhances bone remodeling and facilitates tooth movement. Modified corticotomy techniques involve limited surgical injury to the cortical bone to stimulate accelerated movement while minimizing postoperative morbidity. Frictionless mechanics using T-loops allow controlled canine retraction with reduced frictional resistance between the bracket and archwire.
This single-center randomized controlled clinical trial will enroll 60 patients aged 12 to 30 years who require bilateral extraction of maxillary first premolars as part of orthodontic treatment. Participants will be randomly allocated in a 1:1 ratio to:
Group A: Modified corticotomy-assisted canine retraction with frictionless T-loop mechanics Group B: Conventional frictionless T-loop canine retraction
All participants will be treated using 0.022 × 0.028-inch preadjusted edgewise appliances. Standardized T-loop activation delivering controlled force will be performed at three-week intervals until canine retraction is completed.
External apical root resorption will be assessed by measuring linear changes in root length from the canine cusp tip to the root apex on calibrated pre- and post-retraction panoramic radiographs using digital measurement software. The primary outcome measure will be the mean change in root length between baseline and post-retraction assessments. Statistical analysis will compare the magnitude of root resorption between the two groups.
Healthy volunteers accepted: Yes
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
A surgical procedure in which a buccal flap is elevated and two vertical corticotomy cuts are made in the maxillary cortical bone adjacent to the extraction site to accelerate orthodontic tooth movement.
Orthodontic space closure using 17×25 TMA T-loops activated to deliver approximately 200 g of force for frictionless canine retraction into maxillary first premolar extraction spaces.
Time frame: - Before retraction (baseline) - From baseline to completion of canine retraction (approximately 4-6 months)
External apical root resorption measured as the difference in root length (in millimeters) from canine cusp tip to root apex on calibrated pre-treatment and post-retraction OPG radiographs using ViewBox software.
Time frame: From baseline to completion of canine retraction (approximately 4-6 months)
Difference in mesial and distal root width measured 1 mm short of the root apex on calibrated OPG radiographs before and after canine retraction.
Time frame: At completion of canine retraction (approximately 4-6 months)
SHARPE ET AL. CLASSIFICATION OF EXTERNAL ROOT RESORPTION
0 = No apical root resorption
Contact information is provided by the study sponsor or research team.
Dr. Menal Khurshid, BDS
CONTACT
Prof. Dr. Haroon Shahid Qazi, BDS, MS, MCPS (HPE),
CONTACT
Islamabad Medical and Dental College
Other
Comparison of External Apical Root Resorption in Modified Corticotomy-Assisted and Conventionally Retracted Maxillary Canines Using Frictionless T-Loop Mechanics: A Randomized Controlled Clinical Trial
Acronym: MCA-CR
OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.
View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.