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NCT Number: NCT07395440

Comparison of Quadratus Lumborum Block Types in Open Gynecologic Surgery

This study was conducted to evaluate the effectiveness of Quadratus Lumborum Type 1 and Type 2 blocks on postoperative acute pain in gynecological operations performed with a Pfannenstiel incision.

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Key information

Age range

18 year–80 year

Sex eligibility

Female

Study type

Observational

Primary location

Ankara Etlik City Hospital

Ankara, 06830, Turkey (Türkiye)

About this study

This prospective observational study was conducted to observe and analyze postoperative acute pain outcomes in patients undergoing open gynecologic surgery with a Pfannenstiel incision. The study included patients who received quadratus lumborum block (QLB) techniques as part of routine perioperative analgesic management.

Quadratus lumborum blocks were performed using ultrasound guidance according to standard clinical practice. The block was administered with the patient in the lateral position, and a high-frequency linear ultrasound transducer was used to identify the quadratus lumborum muscle and surrounding anatomical structures. For Quadratus Lumborum Type 1 (lateral) block, local anesthetic was injected at the anterolateral border of the quadratus lumborum muscle. For Quadratus Lumborum Type 2 (posterior) block, local anesthetic was deposited posterior to the quadratus lumborum muscle, within the thoracolumbar fascial plane.

The selection of Quadratus Lumborum Type 1 or Type 2 block was determined solely by the attending anesthesiologist based on routine clinical considerations, surgical characteristics, and patient-related factors. No intervention or regional analgesia technique was assigned by the investigators for the purpose of this study, and study participation did not influence anesthetic management. Participants would have received the same anesthetic and regional analgesia techniques in the same manner and intensity regardless of study enrollment.

Postoperative acute pain outcomes were prospectively collected and analyzed between predefined exposure groups according to the routinely applied quadratus lumborum block technique. The investigators did not modify clinical practice, dosing, timing, or performance of regional anesthesia. All anesthetic and analgesic interventions were provided as part of standard medical care.

This study was approved by the local ethics committee as an observational study and was conducted in accordance with institutional standards of care.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA I-III
  • Female patients aged 18-80
  • Cases undergoing open myomectomy and total abdominal hysterectomy

Exclusion criteria

  • Those who do not want a block
  • Patients who are allergic to local anesthetics
  • Patients with coagulopathy
  • Pregnancy
  • Previous surgery in the area where the block will be applied

Treatment and study plan

Primary outcomes

  1. Reduction of opioid requirement in patients undergoing open myomectomy and total abdominal hysterectomy

    Time frame: from april to may

    It investigates the effectiveness of quadratus lumborum 1 block alone in acute pain, compared to quadratus lumborum 1 and 2 blocks applied together in patients undergoing open myomectomy and total abdominal hysterectomy.

Secondary outcomes

  1. no need for additional analgesia

    Time frame: from 1 may to 15 may

    the first postoperative analgesic consumption in patients undergoing open myomectomy and total abdominal hysterectomy.

Sponsors and collaborators

Lead sponsor

Ankara Etlik City Hospital

Other Gov

Registry information

Official study title

A Prospective Observational Comparison of Quadratus Lumborum Block Techniques in Gynecologic Surgery

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 9, 2026
Registry last updated
Feb 9, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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