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Completed

NCT Number: NCT03297931

Comparison of Pulse Chips and Commercial Snacks on Food Intake, Appetite and Blood Glucose in Healthy Young Adults

Consumers are often forced to eat fast, convenient foods and snacks ("eat on the go") in order to match the pace of their lifestyles. However, these snack options more often than not offer little health benefit to the consumer. In fact, 55% of calories consumed by Canadians are ultra processed foods, which are limited in their nutrient profile and only offer empty calories. Subsequently, these foods lead the consumer to eat more and provides little to no feelings of satiety or satiation. the proposed objectives of the current project are to examine the physiological benefit(s) of consuming readily available pulse snacks and compare them to other commonly consumed snack varieties. This work aims to incentivize consumers to seek out pulses as valuable snacking options and highlight the benefit of including these as alternatives to other energy-dense snacks that lack the nutritional composition of pulses.

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Key information

Age range

18 year–45 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

University of Toronto

Toronto, Ontario, M5S 3E2, Canada

About this study

Hypothesis of the study: Inclusion of pulses as part of a snack will lower appetite and post-prandial glycemia (PPG) in comparison to commercial, commonly consumed non-pulse snacks.

Overall Objective of the study: To investigate and compare the effects of pulse and non-pulse snacks served as chips and dip on appetite and PPG in healthy adults.

Specific objectives of the study: To test the acute effects of different pulse snacks on: 1) PPG and appetite for three hours, and 2) food intake 1 hour following consumption of snacks.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age: ≥18 and ≤45 years
  • BMI: ≥ 18.5 and ≤ 29.9 kg/m2
  • Fasting serum glucose: ≤ 5.6 mmol/L
  • Willing to maintain habitual diet, physical activity pattern, and body weight throughout the trial.
  • Willing to maintain current dietary supplement use throughout the trial. On test days, subject agrees not to take any dietary supplements until dismissal from the Department of Nutritional Sciences. Failure to comply will result in a rescheduled test visit.
  • Willing to abstain from alcohol consumption for 24 h prior to all test visits.
  • Willing to avoid vigorous physical activity for 24 h prior to all test visits.
  • Understanding the study procedures and willing to provide informed consent to participate in the study and authorization to release relevant protected health information to the study investigator.

Exclusion criteria

  • Fasting blood glucose > 5.6 mmol/L
  • Smoking
  • Thyroid problems
  • Previous history of cardiovascular disease, diabetes, liver or kidney disease, inflammatory bowel disease, celiac disease, short bowel syndrome, any malabsorptive syndrome, pancreatitis, gallbladder or biliary disease.
  • Presence of gastrointestinal disorder or surgeries within the past year.
  • Consuming prescription or non-prescription drug, herbal or nutritional supplements known to affect blood glucose or that could affect the outcome of the study as per investigator's judgement.
  • Patients who have undergone bariatric surgery at any point.
  • Known to be pregnant or lactating.
  • Unwillingness or inability to comply with the experimental procedures
  • Known intolerance, sensitivity or allergy to pulses or dairy.
  • Extreme dietary habits (ie. Atkins diet, very high protein diets, etc.).
  • Uncontrolled hypertension (systolic blood pressure ≥ 140 mm Hg or diastolic blood pressure ≥ 90 mm Hg) as defined by the average blood pressure measured at screening.
  • Weight gain or loss of at least 10 lbs in previous three months.
  • Excessive alcohol intake (more than 2 drinks per day or more than 9 drinks per week)
  • Restrained Eaters

Treatment and study plan

Corn Chips + Onion Dip

Dietary Supplement

Non-pulse chip + non-pulse dip

Yellow pea chip + hummus

Dietary Supplement

Novel pulse chip + pulse spread

Pinto bean chip + hummus

Dietary Supplement

Commercial pulse chip + pulse spread

Pinto bean chip + onion dip

Dietary Supplement

Commercial pulse chip + non-pulse spread

Yellow pea chip + onion dip

Dietary Supplement

Novel pulse chip + non-pulse spread

Corn chips + hummus

Dietary Supplement

Non-pulse chip + pulse spread

Primary outcomes

  1. Change in blood glucose levels

    Time frame: Starting at the beginning of each session (0 minutes, before consumption of treatment) and every 15 - 30 minutes up to 190 minutes (time of completion of each session)

    Each participant will attend 6 sessions in total (randomized 6-arm cross-over design)

  2. Subjective appetite

    Time frame: Measured every 15-30 minutes up to 190 minutes

    Measured using Visual Analog Scales (VAS)

  3. Food intake

    Time frame: 65 minutes after completion of treatment, 20 minutes is allocated to allow for pizza consumption

    Food intake is measured by the amount of pizza (in grams) consumed during the 20 minute period (pizza is served ad libitum)

Sponsors and collaborators

Lead sponsor

University of Toronto

Other

Registry information

Official study title

Comparison of Roasted Pulse Snacks, Pulse Chips and Commercial Snacks on Post-prandial Food Intake, Appetite and Glycemic Response in Healthy Young Adults

Important dates

Study start
2017
Primary completion
2023
Study completion
2024
First posted
Sep 29, 2017
Registry last updated
Mar 28, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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