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NCT Number: NCT07483814

Comparison of Postoperative Analgesic Efficacy of Interscalene and Suprascapular Blocks Used in Arthroscopic Shoulder Surgery

The Importance of Postoperative Analgesia in Shoulder Surgery

Shoulder surgery is an orthopedic procedure that can be performed either through open surgery or arthroscopically. Pain following shoulder surgery can lead to adverse outcomes such as decreased functional status, increased consumption of narcotic analgesics, and the development of chronic pain.

Therefore, achieving optimal postoperative shoulder analgesia is important not only for patient comfort and satisfaction but also for promoting functional recovery, preventing chronic pain, and reducing the need for narcotic analgesics. Additionally, minimizing the side effects associated with nerve block techniques used for analgesia is crucial for the overall success of the treatment.

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Key information

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Observational

Primary location

Adnan menderesüniversite Hastanesi

Aydin, Efeler, 09010, Turkey (Türkiye)

About this study

The innervation of the shoulder joint is provided by the axillary, musculocutaneous, subscapular, and suprascapular nerves, all of which originate from the brachial plexus. The suprascapular nerve passes through the suprascapular notch on the superior border of the scapula and supplies motor branches to the rotator cuff muscles. Suprascapular nerve block is widely used in the management of shoulder pain.

Regional anesthesia techniques are among the most effective methods for postoperative analgesia. Peripheral nerve blocks, a subtype of regional anesthesia, are particularly suitable for postoperative pain control in shoulder surgeries due to their ability to provide long-lasting and effective analgesia, reduce opioid requirements and related side effects or dependency, and facilitate recovery by promoting early functional restoration.Interscalene brachial plexus block (ISB) is commonly used for analgesia in shoulder surgery and is considered the gold standard technique. However, ISB also blocks the phrenic nerve (C3-C5), which may result in ipsilateral hemidiaphragmatic paresis (HDP). This can cause respiratory complications, particularly in patients with preexisting pulmonary disease, obstructive sleep apnea, or morbid obesity.

The suprascapular nerve block (SSB), applied at a more distal level of the brachial plexus, preserves the phrenic nerve and thus minimizes the respiratory side effects associated with ISB.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who have provided written informed consent
  • Patients over 18 years of age scheduled for elective shoulder arthroscopy
  • Patients classified as ASA I-II
  • Patients undergoing general anesthesia

Exclusion criteria

  • Patients undergoing shoulder surgery other than arthroscopic procedures (e.g., revision or open surgery)
  • Patients with pre-existing respiratory, cardiac, renal, neurological, or hepatic diseases
  • Presence of neuropathy affecting the brachial plexus
  • Contraindications to peripheral nerve block (e.g., coagulopathy)
  • Known allergy to local anesthetics

Treatment and study plan

rescue analgesia

Other

In the postoperative recovery room, patients with a Numeric Rating Scale (NRS) score of 4 or higher received 100 mg of intravenous tramadol as rescue analgesia. In addition, both groups routinely received 1 g of intravenous paracetamol every 6 hours during their stay in the ward. During ward follow-up, if the NRS score was 4 or higher, 100 mg of intravenous tramadol was administered as needed.

Primary outcomes

  1. The analgesic efficacy of interscalene block (ISB) and suprascapular block (SSB) will be compared in patients undergoing shoulder arthroscopy.

    Time frame: the first 48 hours postoperatively

    It is a pain intensity assessment system based on the patient indicating a point between 0 (no pain) and 10 (unbearable pain) to describe their pain level.

Secondary outcomes

  1. The development of chronic pain following interscalene block (ISB) and suprascapular block (SSB) will be compared in patients undergoing shoulder arthroscopy.

    Time frame: 3 months postoperatively

    Postoperative chronic pain will be evaluated after 3 months using a numerical rating pain scale: 0 (no pain) to 10 (unbearable pain).

Other outcomes

  1. The side effects of interscalene block (ISB) and suprascapular block (SSB) will be compared in patients undergoing shoulder arthroscopy.

    Time frame: the first 48 hours postoperatively

    The number of patients with dyspnea symptoms after suprascapular and interscalene blocks applied after arthroscopic shoulder surgery will be compared.

Sponsors and collaborators

Lead sponsor

Aydin Adnan Menderes University

Other

Registry information

Official study title

Comparison of the Analgesic Effects and Side Effects of Interscalene and Suprascapular Blocks for Pain Control Following Arthroscopic Shoulder Surgery

Important dates

Study start
2024
Primary completion
2027
Study completion
2027
First posted
Mar 19, 2026
Registry last updated
Mar 19, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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