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OpenTrials
Completed

NCT Number: NCT07469410

Comparison of Postoperative Analgesia in Erector Spinae Plane Block (ESPB) v/s Subcostal Transversus Abdominal Plane Block (STAP) in Adults Undergoing Laparoscopic Cholecystectomy.

Postoperative pain after laparoscopic cholecystectomy remains clinically relevant. This double-blinded randomized controlled trial compares the analgesic efficacy of landmark-guided Erector Spinae Plane Block (ESPB) and subcostal transversus abdominis plane (STAP) block in 60 adult patients. Postoperative pain will be evaluated using the Visual Analogue Scale at multiple time points, along with rescue analgesic requirements and time to first analgesic request, to assess the effectiveness of these techniques in resource-limited settings.

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Key information

Conditions

Postoperative Analgesia

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 3

Primary location

Kulsoom Mehmood

Karachi, Pakistan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients are both men and women.
  • Patients aged 18 to 65.
  • Patients are scheduled for a laparoscopic cholecystectomy.
  • Patients with ASA Physical Status I or II. Finally, III.
  • Give consent.

Exclusion criteria

  • Hypersensitivity to local anesthesia.
  • Infection at the block site.
  • Coagulation disorders.
  • BMI above 40kg/m2.
  • Patients with pregnancy.
  • Converted to open surgery.
  • Drain placement.
  • Neurological or psychiatric disorders that impair cooperation.
  • Patients are unwilling to cooperate.

Treatment and study plan

Landmark guided Erector Spinae Block

Drug

Patients will receive a landmark-guided Erector Spinae Plane Block on the right side at T9 level with 30 mL of 0.25% ropivacaine after induction of general anesthesia.

Landmark guided Transversus Abdominis Plane Block

Drug

Patients will receive a landmark-guided Subcostal Transversus Abdominis Plane Block on the right side with 30 mL of 0.25% ropivacaine after induction of general anesthesia.

Primary outcomes

  1. VAS score

    Time frame: From arrival in the post-anesthesia care unit (PACU) through 24 hours postoperatively, assessed at 30 minutes in PACU, and at 6 hours, 12 hours, and 24 hours after surgery.

    Postoperative pain intensity measured using the Visual Analog Scale (VAS), a 10-cm scale ranging from 0 to 10, where 0 = no pain and 10 = worst imaginable pain. Higher scores indicate worse pain.

Secondary outcomes

  1. need for rescue analgesia and time for first analgesic request.

    Time frame: From completion of surgery through 24 hours postoperatively.

    Proportion of patients requiring rescue analgesia during the postoperative period.

Sponsors and collaborators

Lead sponsor

Patel Hospital, Pakistan

Other

Registry information

Official study title

Comparison Of Postoperative Analgesia In Landmark Guided Erector Spinae Plane Block And Subcostal Transversus Abdominis Plane Block In Laparoscopic Cholecystectomy; A Randomized Controlled Trial

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Mar 13, 2026
Registry last updated
Mar 13, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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