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NCT Number: NCT04677348

Comparison of PENG Block and FICB in Hip Fracture Patients

Fascia iliaca compartment block (FICB) has been considered the block of choice for patients with hip fracture. However, pericapsular nerve group (PENG) block, one of the relatively newly-developed blocks, could be also used for analgesia in patients with hip fracture. Since PENG block could block the accessory obturator nerve, PENG block might have greater analgesic effects compared to FICB theoretically. However, the comparison of these two blocks in patients with hip fracture has not performed in clinical setting. Thus, we aimed to compare the analgesic effect of PENG block and FICB.

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Key information

Conditions

Hip Fractures Femoral Fractures Fractures, Bone Hip Injuries Leg Injuries Regional Anesthesia Wounds and Injuries

Age range

19 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Asan Medical Center

Seoul, 05505, South Korea

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • ASA PS 1-4
  • age: ≥19
  • baseline pain score (associated with hip fracture): ≥4

Exclusion criteria

  • patients who do not agree to participate in this study
  • patients with uncontrolled hypertension, hyperthyroidism, severe dementia
  • allergic to ropivacaine
  • contraindicated to spinal anesthesia due to coagulopathy, severe aortic stenosis/mitral stenosis, or active infection on lumbar region
  • patients who are considered ineligible with any other reason by investigators

Treatment and study plan

pericapsular nerve group (PENG) block

Procedure

ultrasound-guided PENG block with 0.3% ropivacaine 20cc

Fascia iliaca compartment block (FICB)

Procedure

ultrasound-guided suprainguinal FICB with 0.3% ropivacaine 30cc

Primary outcomes

  1. Efficacy of each block (Pain score)

    Time frame: before surgery

    We will assess the dynamic pain (pain during a movement) using NRS before and 20-30min after applying the assigned block. Then, we will calculate the change of NRS at the two time-points.

    NRS: Numerical rating scale (0, no pain; 10, the worst pain imaginable)

Secondary outcomes

  1. change of blood pressure (systolic, diastolic, mean blood pressure)

    Time frame: before surgery

    We will evaluate the blood pressure before and 20-30min after applying the assigned block. Then, we will calculate the change of blood pressure at the two time-points.

  2. postoperative pain score

    Time frame: postoperative 6, 24, 48hours

    resting and dynamic pain using NRS at postoperative 6, 24, 48hours

    NRS: Numerical rating scale (0, no pain; 10, the worst pain imaginable)

  3. postoperative opioid consumption

    Time frame: postoperative 24, 48hours

    morphine-equivalent dose

  4. postoperative motor function

    Time frame: postoperative 6, 24, 48hours

    motor function of quadriceps femoris

    grade5: normal power grade4: movement possible against some resistance grade3: movement against gravity but not resistance grade2: movement possible if gravity eliminated grade1: flicker of contraction possible grade0: complete paralysis

  5. change of heart rate

    Time frame: before surgery

    We will evaluate the heart rate before and 20-30 min after applying the assigned block. Then, we will calculate the change of heart rate at the two time-points.

Sponsors and collaborators

Lead sponsor

Asan Medical Center

Other

Registry information

Official study title

Comparison of Analgesic Effect of Pericapsular Nerve Group Block and Suprainguinal Fascia Iliaca Compartment Block on Dynamic Pain in Patients Undergoing Hip Fracture Surgery: a Randomized Controlled Trial

Important dates

Study start
2021
Primary completion
2022
Study completion
2022
First posted
Dec 21, 2020
Registry last updated
Mar 23, 2022

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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