Skip to main content
OpenTrials
Recruiting

NCT Number: NCT07550686

Comparison of Patient Understanding and Anxiety According to the Delivery Method of Educational Videos

This study aims to evaluate whether a generative artificial intelligence (AI)-based educational video is more effective than a conventional video in improving patient understanding and reducing anxiety before radiation therapy.

In this prospective, randomized controlled study, participants will be assigned in a 1:1 ratio to either an AI-based avatar video group or a conventional video group consisting of PowerPoint slides with voice narration. Both videos will be standardized to have similar duration (approximately 5 minutes), identical key messages, and the same summary points.

After providing informed consent, participants will complete questionnaires before and after watching the assigned video, as well as during the first week of treatment. Outcomes will include anxiety levels, knowledge comprehension, and satisfaction with the educational video.

A total of 136 patients scheduled to undergo radiation therapy will be enrolled from two institutions. The findings of this study are expected to provide evidence on the effectiveness of AI-based educational tools in enhancing patient education and reducing pre-treatment anxiety.

Recruiting

Interested in participating?

Request Info

Key information

Conditions

Radiotherapy Patient Education

Age range

20 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Yongin Severance Hospital

Yongin-si, 365, South Korea

Location status: Recruiting

Location contact

Hwakyung BYUN, professor

CONTACT

[email protected]

03151898891

About this study

This study is a prospective, randomized, parallel-group trial designed to evaluate the effectiveness of a generative artificial intelligence (AI)-based educational video compared with a conventional video in patients undergoing radiation therapy.

Participants will be randomly assigned in a 1:1 ratio to one of two groups: (A) an AI-based avatar video group or (B) a conventional video group consisting of PowerPoint slides with voice narration. Both videos will be standardized to ensure comparable duration (approximately 5 minutes), identical core content, and equivalent summary points to minimize variability in information delivery.

After providing informed consent, participants will be asked to complete structured questionnaires at three time points: before viewing the video (baseline), immediately after viewing the video, and during the first week of radiation therapy. The assessments will include measures of anxiety, knowledge comprehension, and satisfaction with the educational material. Baseline assessments will be used as reference values for evaluating changes over time.

The primary objective is to compare post-intervention anxiety levels between the two groups. Secondary objectives include comparisons of knowledge comprehension, satisfaction with the educational video, and changes in anxiety over time.

Statistical analyses will be performed based on the intention-to-treat principle. Descriptive statistics will be used to summarize baseline characteristics. Changes in outcomes over time and between groups will be analyzed using appropriate statistical models for repeated measures. Missing data will not be imputed; analyses will be conducted using available data for each outcome measure.

This study will be conducted at two institutions and aims to provide evidence on whether AI-based educational tools can improve patient understanding and reduce anxiety in the clinical setting.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age ≥ 20 years
  • Patients scheduled for radiotherapy
  • Ability to watch video and comprehend audio, as assessed by the investigator
  • ECOG performance status 0-1

Exclusion criteria

  • Patients unable to complete questionnaires due to cognitive impairment or psychiatric disorders

Treatment and study plan

AI-based educational video

Other

Standardized 5-minute educational video delivered via AI-generated avatar to explain radiotherapy procedures, expected side effects, and self-care information. Designed to improve patient understanding and reduce anxiety.

Other names: Generative AI avatar video

Conventional educational video (PPT + narration)

Other

5-minute educational video using PowerPoint slides with voice narration covering identical content as the AI-based video, including radiotherapy procedures, side effects, and self-care information.

Other names: Slide-based narrated video

Primary outcomes

  1. Anxiety score (APAIS)

    Time frame: T1(Immediately after the intervention /during the pre-treatment consultation visit)

    Anxiety will be measured using the Amsterdam Preoperative Anxiety and Information Scale (APAIS) (total score range: 6-30; higher scores indicate greater anxiety). Change from baseline will be analyzed using a linear mixed model.

Secondary outcomes

  1. Anxiety level (K-HADS-A)

    Time frame: T1(Immediately after the intervention (during the pre-treatment consultation visit)

    Anxiety will be measured using the Korean version of the Hospital Anxiety and Depression Scale - Anxiety subscale (K-HADS-A) (score range: 0-21; higher scores indicate greater anxiety). Change from baseline will be analyzed using a linear mixed model.

  2. Anxiety level (APAIS, K-HADS-A)

    Time frame: T2(During the first week of treatment)

    Anxiety will be measured using both APAIS an d K-HADS-A during the first week of treatment. Baseline scores assessed

    Anxiety will be measured using the Amsterdam Preoperative Anxiety and Information Scale (APAIS) (6-30; higher = greater anxiety) and the Korean version of the Hospital Anxiety and Depression Scale - Anxiety subscale (K-HADS-A) (0-21; higher = greater anxiety). Change from baseline will be analyzed using a linear mixed model.

  3. Knowledge score

    Time frame: T1(Immediately after the intervention /during the pre-treatment consultation visit) and T2(during the first week of treatment)

    Knowledge will be assessed using a structured questionnaire (score range: 0-10; higher scores indicate better knowledge). Change from baseline will be analyzed using a linear mixed model.

  4. Satisfaction score

    Time frame: T1(Immediately after the intervention /during the pre-treatment consultation visit) and T2(during the first week of treatment)

    Participant satisfaction with the educational intervention will be assessed

    Satisfaction will be assessed using a standardized questionnaire (score range: 0-10; higher scores indicate greater satisfaction). Change over time will be analyzed using a linear mixed model.

Study contacts

Contact information is provided by the study sponsor or research team.

HwaKyung Byun, MD, PhD

CONTACT

[email protected]

+82-31-5189-8166

Sponsors and collaborators

Lead sponsor

Yonsei University

Other

Collaborators

  • Severance Hospital

Registry information

Official study title

Comparison of Patient Understanding and Anxiety According to the Delivery Method of Educational Videos: A Prospective Randomized Study in Radiotherapy Patients

Important dates

Study start
2025
Primary completion
2027
Study completion
2027
First posted
Apr 24, 2026
Registry last updated
Apr 29, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Related clinical trials

Published trials that share one or more normalized conditions with this study.