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Completed

NCT Number: NCT06170931

Comparison Of Outcomes After Knee Arthroplasty Using Posterior-Substituting Versus Cruciate-Retaining Prostheses

Total knee replacement is used in the treatment of patients with knee arthritis, rheumatoid arthritis and other knee disorders. Today, there are basically two designs; It cuts the posterior cruciate ligament (PS) and protects the posterior cruciate ligament (CR). Although there is no clear study suggesting which design is better, research on this subject has increased recently. the investigators aim is to define the superiority of these two designs over each other. Preoperative and postoperative joint range of motion examinations were performed on both knees separately. WOMAC and OXFORD scores were examined separately for both knees.

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Key information

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bezmialem Vakıf University

Istanbul, Fatih, 34093, Turkey (Türkiye)

About this study

Total knee arthroplasty is used to treat patients with osteoarthritis, rheumatoid arthritis, and other knee disorders. Today, there are basically two primary designs; posterior cruciate Substituting (PS) and protects the posterior cruciate -Retaining (CR). However, it is still controversial which approach is good, as both CR and PS have advantages and disadvantages. Proponents of the posterior cruciate retaining system argue that it provides natural stability, wider joint range of motion, better proprioception, and better knee kinematics. In addition, proponents of the posterior cruciate substituting system argue that it provides more harmonious articulation and a wider flexion range.

As a result, although there is no clear study suggesting which design is better, research on this subject has increased recently. Our aim is to define the superiority of these two designs over each other.

Patients with the same stage of knee osteoarthritis in both knees were selected. Total knee arthroplasty was performed in the same session by making the appropriate design for the appropriate knee simultaneously. Preoperative and postoperative joint range of motion examinations were performed on both knees separately. WOMAC and OXFORD scores were examined separately for both knees.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients with primary osteoarthritis of both knees
  • Patients with secondary osteoarthritis of both knees

Exclusion criteria

  • Patients with primary osteoarthritis in both knees and undergoing unilateral knee prosthesis
  • Patients with secondary osteoarthritis in both knees and who underwent unilateral knee prosthesis
  • Patients with primary osteoarthritis in both knees and who underwent bilateral knee prosthesis in different sessions
  • Patients with secondary osteoarthritis in both knees and who underwent bilateral knee prosthetics in different sessions.

Treatment and study plan

posterior cruciate ligament-retaining prostheses

Procedure

Posterior cruciate ligament protective approach in patients with knee osteoarthritis

posterior cruciate ligament-substituting prostheses

Procedure

Posterior cruciate ligament transection approach in patients with knee osteoarthritis

Primary outcomes

  1. Range of motions

    Time frame: 3 year

    Preoperative and postoperative knee flexion and extension degrees of the patients were measured.

Secondary outcomes

  1. WOMAC Score (Score from 0 to 100)

    Time frame: 3 year

    Preoperative and postoperative WOMAC score of the patients were examined.

  2. OXFORD Knee Score(Score from 0 to 60)

    Time frame: 3 year

    Preoperative and postoperative OXFORD score of the patients were examined.

Sponsors and collaborators

Lead sponsor

Bezmialem Vakif University

Other

Registry information

Official study title

Comparison Of Outcomes After Bilateral Simultaneous Total Knee Arthroplasty Using Posterior-Substituting Versus Cruciate-Retaining Prostheses

Important dates

Study start
2021
Primary completion
2023
Study completion
2024
First posted
Dec 14, 2023
Registry last updated
Dec 6, 2024

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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