Comparison Of Outcome Of Microneedling With Autologous PRP Vs Microneedling With Topical Insulin In Treatment Of Post Acne Atrophic Scars.

Microneedling with topical INSULIN is a simple, effective tool for building body's new collagen layers and thus an alternative to all erosive techniques such as lasers, peels. The skin responds to fine punctures with the release of growth factors. 8 It is a safe procedure that can be performed in the office without complications, with a good cost-benefit because it is economically viable without any effect on patient's daily activities. 9

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Key information

Conditions

Atrophic Acne Scars

Age range

20 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Phase 2

Primary location

JPMC

Karachi, Sindh, Pakistan

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

postacne atrophic scars ≥ 2 on Goodman and Baron's acne scar-grading system
Either gender.
Age 20-50 years.

Exclusion criteria

lactation and pregnancy
skin cancers and infection
photosensitivity like SLE ,XP
use of RETINOIDS in last 6 months.

Treatment and study plan

PRP( platelet rich plasma) and Insulin human

Drug

Microneedling with autologus PRP reduces inflammationin acne scars. Insulin human is a new topical drug which is used nowadays for acne scars as it is more effective in producing collagen formation as well as new blood vessel formation

Primary outcomes

Efficacy of Topical Insulin R with microneedling versus Platelets rich plasma in atrophic acne scars

Time frame: Efficacy will be assesed upto 4 months.

Efficacy will be assessed by using Goodman and Baron Qualitative Scar Grading System

Sponsors and collaborators

Lead sponsor

Jinnah Postgraduate Medical Centre

Other Gov

Registry information

Official study title

Comparison Of The Outcome Of Treatment of Microneedling With Autologous Platelet- Rich -Plasma Versus Microneedling With Topical Insulin In The Treatment Of Post Acne Atrophic Scars.

Important dates

Study start: 2022
Primary completion: 2022
Study completion: 2023
First posted: Aug 21, 2023
Registry last updated: Aug 21, 2023

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

Published trials that share one or more normalized conditions with this study.

Completed