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Completed

NCT Number: NCT07416487

Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor

There are gaps in the local data regarding the comparative effectiveness of Foley catheter versus misoprostol for induction of labor (IOL). Therefore, the current study was planned with the objective of comparing the mean induction-to-delivery interval of Foley catheter versus misoprostol for IOL in singleton term pregnancy.

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Key information

Conditions

Labor

Age range

18 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

D.G. Khan Medical College/Allama Iqbal Teaching Hospital

Dera Ghazi Khan, Punjab Province, 32200, Pakistan

About this study

Although systematic reviews and meta-analyses have compared the effectiveness and safety of pharmacologic, nonpharmacologic, mechanical, and combined methods of cervical ripening and labor induction, the optimal method of IOL is still debatable. The findings would be helpful in further assessing the conflicting evidence and furnishing the limited data regarding the use of Foley catheters or misoprostol in patients undergoing IOL from local setups.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pregnant females
  • 18-40 years
  • With a singleton term pregnancy (37-41) weeks
  • Parity < 4
  • Vertex presentation (on ultrasound scan)
  • Intact membranes (on history and clinical examination)
  • Going through labor induction

Exclusion criteria

  • With a previous uterine surgery
  • Non-reassuring cardiotocography (CTG)
  • Oligohydramnios (on ultrasound scan)
  • Intrauterine growth restriction (IUGR) (on ultrasound scan)
  • Abruptio placenta (on ultrasound scan).

Treatment and study plan

Misoprostol

Drug

Women received intravaginal misoprostol 25 μg 4 hours apart, up to a maximum of four doses.

foley catheter

Device

An intracervical Foley catheter (16 F) was inserted into the patients. The balloon was inflated with 30 mL of sterile normal saline solution and was kept in place until it expelled spontaneously.

Primary outcomes

  1. Delivery of the fetus

    Time frame: 24 hours

    Induction-to-delivery interval was calculated from the insertion of the Foley catheter or misoprostol until the delivery of the fetus in hours.

Sponsors and collaborators

Lead sponsor

Muhammad Aamir Latif

Other

Registry information

Official study title

Comparison of Outcome of Foley Catheter Versus Misoprostol for Induction of Labor at Term Pregnancy

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Feb 18, 2026
Registry last updated
Feb 18, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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