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OpenTrials
Completed

NCT Number: NCT07200076

Comparison of Mean Duration of Post Operative Analgesia Following QL-2 Block vs QL-3 Block Using Ropivacain 0.25% in Patients Undergoing Unilateral Inguinal Hernia Repair

To compare the mean dulation of post operative analgesia following QL2 block (posterior quadratus lumborum block) and the QL3 block (transmuscular quadratus lumborum block) using ropivacaine 0.25% in patients undergoing unilateral inguinai hernia repair.

Rationale of the proposed study is to find an optimal approach for quadratus lumborum block (QLB) in the context of local population as no local study has already been carried out for our population. The study seeks to determine which approach provides superior postoperative pain relief and aspires to establish a clear rationale for the application of one technique over the other in local population. By uncovering the strengths and limitations of each approach, the study intends to guide local clinicians in making informed decisions for optimizing postoperative pain management strategies. The outcomes of this study are anticipated to have a substantial impact on clinical practice, potentially leading to improved patient outcomes, reduced opioid consumption, and enhanced patient comfort following inguinal hernia repair surgeries in local settings.

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Key information

Age range

18 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Bahawal Victoria Hospital, Bahawalpur

Bahawalpur, Punjab Province, 63100, Pakistan

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Age between 18 and 50 years ASA status 1 or 2 Scheduled for unilateral inguinal hernia repair under General Anaesthesia

Exclusion criteria

  • Patient refusal Patients with pre-existing coagulation abnormalities INR more thnn 1.5 Patients with Strangulated hernia Hypersensitivity to local anaestiretics. Local infection at procedure sito.

Treatment and study plan

Quadratus Lumborum (QL) Block

Procedure

In the QLB-2 approach, a needle will be inserted in-plane from anterior to posterior, directed towards the posterior QL muscle border, and a 20 ml solution of 0.25% ropivacaine will be injected.

For the QLB-3 approach, the needle will be inserted in-plane from anterior to posterior, traversing the QL muscle's proper fascia to target the plane between the QL and PM muscles, and a 20 ml solution of 0.25% ropivacaine will be injected.

Primary outcomes

  1. Change in systolic Blood pressure

    Time frame: Baseline, 30 minutes, 2 hours, 4 hours, 8 hours, 12 hours 24 hours

  2. Mean duration of analgesia

    Time frame: Baseline, 30 minutes, 2 hours, 4 hours, 8 hours, 12 hours, 24 hours

    assessed using the Visual Analog Score (VAS) ranging tiom 0-10 (0= no pain, l0= the most severe unbearable pain)

Sponsors and collaborators

Lead sponsor

Quaid-e-Azam Medical College

Other

Registry information

Important dates

Study start
2024
Primary completion
2024
Study completion
2025
First posted
Sep 30, 2025
Registry last updated
Oct 6, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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