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NCT Number: NCT06857162

Comparison of Maternal Hemodynamics During Spinal Anesthesia with Different Cesarean Delivery Positioning

Cesarean delivery is a common surgical procedure, and maintaining maternal hemodynamic stability during the procedure is crucial for both maternal and fetal outcomes . Hemodynamic instability, such as hypotension following spinal anesthesia, is a frequent complication and can lead to adverse maternal and neonatal outcomes. Traditionally, after spinal anesthesia, women are positioned supine, sometimes with a slight left lateral tilt to mitigate the risk of aortocaval compression . However, recent studies and clinical observations suggest that delayed supine positioning-keeping the patient in a sitting or semi-sitting position for a period following spinal anesthesiamay improve hemodynamic stability. These alternative positions may help to mitigate the abrupt drop in blood pressure commonly seen after spinal anesthesia by allowing for a more gradual redistribution of blood volume . Understanding the optimal positioning strategy could lead to improved clinical protocols that enhance maternal and fetal safety. By comparing immediate supine positioning with delayed supine positioning (in sitting and semi-sitting positions), this study aims to provide evidence on which positioning strategy offers the best hemodynamic outcomes.

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Key information

Age range

20 year–40 year

Sex eligibility

Female

Study type

Interventional

Phase

Not applicable

Primary location

Aswan University Hospital

Aswān, Aswan Governorate, Egypt

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Pregnant women scheduled for elective cesarean delivery.
  • Age between 18 and 40 years.
  • ASA (American Society of Anesthesiologists) physical status II.

Exclusion criteria

  • Emergency cesarean delivery.
  • Pre-existing cardiovascular disease.
  • Severe preeclampsia or eclampsia.
  • Multiple pregnancies.
  • Known fetal anomalies.

Treatment and study plan

Positioninng during Cs

Behavioral
  • Group A (N=72): Immediate Supine Position (Control):

Immediately after administering spinal anesthesia, participants will be placed in a supine position. To reduce the risk of aortocaval compression, a slight left lateral tilt (approximately 15 degrees) will be applied. This is the traditional positioning method and serves as the control group for comparison.

  • Group В (N=72): Sitting Position:

After spinal anesthesia, participants will be positioned in a sitting position with the ack supported at a 90-degree angle for the first 2 minutes. Knees will be bent, and feet will be supported.

  • Group С (N=72): Semi-Sitting Position:

After spinal anesthesia, participants will be positioned in a semi-sitting position with the back supported at the back supported at for the first 2 minutes.

Similar to the sitting position, knees and feet will be flat.

Primary outcomes

  1. To compare the incidence and severity of hypotension in immediate supine, sitting, and semi-sitting positions during cesarean delivery.

    Time frame: 9 Months

Study contacts

Contact information is provided by the study sponsor or research team.

Ahmed Yousef Mohamed, Resident of Anesthesia

CONTACT

[email protected]

+201112842063

Sponsors and collaborators

Lead sponsor

Aswan University

Other

Collaborators

  • Aswan University Hospital

Registry information

Important dates

Study start
2025
Primary completion
2025
Study completion
2025
First posted
Mar 4, 2025
Registry last updated
Mar 19, 2025

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.