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NCT Number: NCT07678814

Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids

Hemorrhoidal disease is one of the most common anorectal disorders. Conventional Milligan Morgan Hemorrhoidectomy remains the standard treatment but is associated with considerable postoperative pain. Laser Hemorrhoidoplasty has emerged as a minimally invasive alternative. This randomized controlled trial compares postoperative pain, patient satisfaction, and hospital stay between Laser Hemorrhoidoplasty and conventional hemorrhoidectomy in patients with Grade II and Grade III hemorrhoids.

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Key information

Conditions

Hemorrhoids Second Degree Behavior Health Behavior Hemorrhoids Third Degree Internal Hemorrhoids Neurologic Manifestations Pain Pain, Postoperative Pathologic Processes Pathological Conditions, Signs and Symptoms Patient Satisfaction Postoperative Complications Signs and Symptoms Treatment Adherence and Compliance

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Jinnah Hospital, Lahore.

Lahore, Punjab Province, Pakistan

About this study

This single-center randomized controlled trial was conducted in the Department of Surgery, Jinnah Hospital Lahore. Ninety-six patients diagnosed with Grade II or Grade III hemorrhoids were randomized into two equal groups.

Group A underwent Laser Hemorrhoidoplasty.

Group B underwent conventional Milligan Morgan Hemorrhoidectomy.

Patients were followed postoperatively for pain assessment using the Visual Analogue Scale (VAS), hospital stay, and patient satisfaction using a structured Likert-scale questionnaire.

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Age ≥18 years Grade II hemorrhoids Grade III hemorrhoids Both genders

Exclusion criteria

Rectal prolapse Anal fissure Anorectal malignancy Pregnancy or lactating mothers

Treatment and study plan

Laser Hemorrhoidoplasty

Procedure

Patients randomized to the intervention group underwent Laser Hemorrhoidoplasty under spinal anesthesia. A diode laser probe was introduced into the hemorrhoidal tissue through a small mucosal entry point under direct visualization using an anoscope. Controlled laser energy was delivered submucosally to achieve coagulation, shrinkage, and fixation of the hemorrhoidal cushions while preserving the surrounding anoderm and mucosa. The procedure was performed according to standard surgical protocols with the aim of reducing postoperative pain, bleeding, and recovery time.

Milligan Morgan Hemorrhoidectomy

Procedure

Patients randomized to the control group underwent conventional open Milligan Morgan Hemorrhoidectomy under spinal anesthesia. The hemorrhoidal pedicles were identified, ligated, and excised using standard surgical techniques. The wounds were left open with preservation of mucocutaneous bridges between excision sites. Hemostasis was achieved as required. Patients received routine postoperative care and follow-up according to institutional protocols.

Primary outcomes

  1. Postoperative Pain

    Time frame: Post Operative period: (6) Six Hourly in first 48 Hours, at 1 week post operative period & at 1 month post operatively.

    Pain measured using Visual Analogue Scale (VAS).

  2. Patient Satisfaction

    Time frame: 1 month postoperative

    Patient satisfaction assessed using Likert-scale questionnaire.

Sponsors and collaborators

Lead sponsor

Allama Iqbal Medical College

Other

Registry information

Official study title

Comparison of Laser Hemorrhoidoplasty Versus Conventional Milligan Morgan Hemorrhoidectomy in Grade II and III Hemorrhoids: A Randomized Controlled Trial

Acronym: LHP-MMH

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Jul 1, 2026
Registry last updated
Jul 1, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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