Mughal Eye Hospital Trust
Lahore, Punjab Province, 54000, Pakistan
NCT Number: NCT07198126
Pterygium, often called "surfer's eye," is a common eye condition in which a raised, fleshy growth of tissue extends from the white part of the eye onto the clear cornea. This growth can cause redness, irritation, blurred vision, and, in advanced cases, changes in the curvature of the cornea leading to distorted vision (astigmatism). The condition is more frequent in people exposed to sunlight, dust, and dry environments.
The standard treatment for symptomatic pterygium is surgical removal. However, simple removal has a high chance of recurrence. To reduce this risk, surgeons commonly use a technique called conjunctival autograft transplantation, where a small piece of the patient's own conjunctiva is placed over the area after excision. This method not only lowers the recurrence rate but may also improve vision by reducing corneal irregularities.
This study is designed to measure the changes in corneal curvature (keratometric readings) before and after pterygium excision with conjunctival autograft transplantation. By comparing preoperative and postoperative measurements, the study aims to determine how much this surgery improves corneal shape and reduces astigmatism.
The hypothesis is that pterygium excision with conjunctival autograft transplantation will lead to a significant improvement in keratometric readings and reduce irregular astigmatism, thereby improving visual quality.
This research will provide local evidence of the effectiveness of this procedure and help guide treatment strategies for patients suffering from pterygium-related visual problems.
Interested in participating?
Request Info30 year–70 year
All sexes
Interventional
Not applicable
Lahore, Punjab Province, 54000, Pakistan
Healthy volunteers accepted: No
Only the study team can determine whether someone qualifies for participation.
Inclusion criteria
Exclusion criteria
Excision of primary Grade II or Grade III pterygium Conjunctival autograft harvested and transplanted at the excision site Graft secured with sutures
Time frame: Baseline (pre-operative) and 1 month post-operative.
Keratometric readings, including the flat meridian (K1) and steep meridian (K2) of the anterior corneal surface, will be measured using a manual keratometer. The mean change in K-readings (measured in diopters) from baseline (pre-operative) to post-operative assessment will be calculated to evaluate corneal curvature improvement following pterygium excision with conjunctival autograft.
Time frame: Baseline (pre-operative) and 1 month post-operative.
Astigmatism will be measured using an automated refractometer. Both type (regular/irregular, with-the-rule/against-the-rule) and degree of astigmatism (in diopters) will be recorded. The reduction in astigmatism from baseline to post-operative follow-up will be assessed.
Mughal Eye Trust Hospital
Other
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View the official ClinicalTrials.gov record (opens in a new tab)This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.
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