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OpenTrials
Completed

NCT Number: NCT02726373

Comparison of Intermittent vs. Continuous Walking in MS

Objective: To compare effects of an intermittent and continuous walking program on walking endurance and fatigue in people with multiple sclerosis (MS).A randomized crossover prospective method was used.The intervention consisted of eight 6-minute-long walks (2x/week for 4 weeks). The continuous condition consisted of 6 continuous minutes of walking. The intermittent condition consisted of three 2-minute bouts with 2-minute rests. After a 4-week detraining period, participants performed the second training condition.

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Key information

Conditions

Multiple Sclerosis, Endurance Autoimmune Diseases Autoimmune Diseases of the Nervous System Demyelinating Autoimmune Diseases, CNS Demyelinating Diseases Immune System Diseases Multiple Sclerosis Nervous System Diseases

Age range

18 year–65 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Positive diagnosis of MS
  • Ambulatory for at least 6 minutes with or without an assistive device (e.g. cane, crutches or orthotics)
  • Ability to read, understand, and sign an informed consent form

Exclusion criteria

  • Evidence of exacerbation in the prior three months as defined by a treating physician
  • Orthopedic or cardiovascular condition that would interfere with ability to walk for 6 continuous minutes,
  • Currently being on an active physical rehabilitation program

Treatment and study plan

type of walking

Other

Subjects walked either intermittently or continuously twice a week for 4 weeks, then crossed over

Primary outcomes

  1. Pre to post change in 6 Minute walk test distance

    Time frame: 4 weeks

Secondary outcomes

  1. Visual Analog Scale of fatigue

    Time frame: 4 weeks

    Measurements to be taken at baseline and after each 4 week intervention

Sponsors and collaborators

Lead sponsor

Hunter College of City University of New York

Other

Registry information

Official study title

The Effect of Intermittent vs. Continuous Walking Training on Walking Endurance and Fatigue in People With Multiple Sclerosis: a Randomized, Crossover Trial.

Important dates

Study start
2013
Primary completion
2014
Study completion
2014
First posted
Apr 1, 2016
Registry last updated
Apr 4, 2016

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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