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NCT Number: NCT06875830

Comparison of Immediate Implant Placement With Titanium Mesh Versus Collagen Membrane in Type II Socket:

Statement of the problem: Immediate implant placement is faced with several problems. One of the most important issues is dealing with defects in the buccal plate of bone in the esthetic zone.

Aim: The aim of this study is to assess the buccal bone thickness after augmentation with titanium mesh and xenograft upon flapless immediate implant placement.

Recruiting

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Key information

Age range

21 year–50 year

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Faculty of oral & dental Medicine,Misr international University

Cairo, Heliopolis - Cairo, 123456, Egypt

Location status: Recruiting

Location contact

Ahmed H Farid, lecturer

CONTACT

[email protected]

Zeinab H AbdelRahman, lecturer

CONTACT

[email protected]

01221334637

About this study

Statement of the problem: Immediate implant placement is faced with several problems. One of the most important issues is dealing with defects in the buccal plate of bone in the esthetic zone.

Aim: The aim of this study is to assess the buccal bone thickness after augmentation with titanium mesh and xenograft upon flapless immediate implant placement.

Materials and Methods: This parallel arm, randomized controlled clinical trial will involve systemically free patients with remaining roots or badly decayed teeth in the anterior region and buccal bone deficiency requiring implant placement. They will be randomly allocated to two equal groups. Group A (test group, n=10) will receive immediate implants (grafting with xenograft covered by titanium mesh covered by collagen membrane), while group B (test group, n=10) will receive immediate implants (grafting with xenograft covered by collagen membrane). The parameters ( buccal bone thickness & soft tissue thickness will be assessed at 6 & 12 months. Postoperative pain and swelling will be recorded daily by the patient for the 1st two weeks post surgically. Postoperative medication will be prescribed to the patient and postoperative instructions will be explained in detail. Follow-up will be performed to assess the parameters and to ensure performing proper oral hygiene. Data collected will be tabulated and statistically analyzed.

Who can participate

Healthy volunteers accepted: Yes

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • Patients who have at least one remaining root or badly decayed tooth in anterior maxilla.
  • Systemically free patients (American Society of Anesthesiologists I; ASA I)
  • Patients aged from 21 to 50 years old
  • Buccal bone partial deficiency (extraction socket type II)
  • Good oral hygiene
  • Accepts the follow-up period (cooperative patients)
  • Patient accepts to provides an informed consent

Exclusion criteria

  • Patients with habits that may jeopardize the implant longevity and affect the results of the study such as parafunctional habits such as bruxism
  • Smokers
  • Pregnant and lactating females

Treatment and study plan

Collagen membrane

Procedure

augmentation of the buccal plate of bone with xenograft and collagen membrane

titanium mesh

Procedure

augmentation of the buccal plate of bone with xenograft and titanium mesh

Primary outcomes

  1. Buccal bone thickness

    Time frame: at baseline, 6 and 12 months

    assessment of the Buccal bone thickness in mm using CBCT

Secondary outcomes

  1. Soft tissue thickness

    Time frame: at baseline 6 and 12 months

    Soft tissue thickness will be assessed in mm using volumetric analysis method

  2. Keratinized tissue width

    Time frame: at baseline, 6 and 12 months

    measurement of the keratinized tissue width in mm using periodontal probe

Study contacts

Contact information is provided by the study sponsor or research team.

Ahmed H Farid, Masters

CONTACT

[email protected]

Hani El Nahas, PhD

CONTACT

[email protected]

+201221334637

Sponsors and collaborators

Lead sponsor

Misr International University

Other

Registry information

Official study title

Comparison of Flapless Immediate Implant Placement With Titanium Mesh Versus Immediate Implants Placement With Collagen Membrane in Type II Socket: A Randomized Clinical Trial

Important dates

Study start
2025
Primary completion
2026
Study completion
2026
First posted
Mar 13, 2025
Registry last updated
Jul 6, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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