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NCT Number: NCT07418853

Comparison of Goniotomy Device Outcomes in Combined Phacoemulsification-goniotomy Surgeries

The goal of this study is to determine of one of three different devices to perform goniotomy to treat glaucoma at the time of cataract surgery is more or less effective than the others. The primary outcomes are to compare intraocular pressure control and glaucoma medication use up to 6 months after surgery. Participants will under combined cataract surgery and goniotomy. They will have post-operative follow up visits at 1 day, 1 week, 1 month, 3 months, and 6 month

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Key information

Conditions

Open Angle Glaucoma (OAG) Eye Diseases Glaucoma Glaucoma, Open-Angle Ocular Hypertension Primary Open Angle Glaucoma (POAG) Secondary Open Angle Glaucoma

Age range

18 year and older

Sex eligibility

All sexes

Study type

Interventional

Phase

Not applicable

Primary location

Henry Ford Health

Detroit, Michigan, 48202, United States

Location contact

Brian Florek, MD

SUB_INVESTIGATOR

Calvin Robbins, MD

CONTACT

[email protected]

313-916-3260

Candice Yousif, MD

SUB_INVESTIGATOR

David A Crandall, MD

CONTACT

[email protected]

248-661-5100

Melisa Nika, MD

SUB_INVESTIGATOR

Nauman Imami, MD

SUB_INVESTIGATOR

Paul Baciu, MD

SUB_INVESTIGATOR

Salma Noorulla, MD

SUB_INVESTIGATOR

Uma Jasty, MD

SUB_INVESTIGATOR

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

Adults ≥ 18 years old

  • Diagnosed with primary or secondary open-angle glaucoma (e.g., POAG, pigmentary, pseudoexfoliative)
  • Scheduled for phacoemulsification with planned goniotomy
  • Able to provide informed consent

Exclusion criteria

  • Angle-closure glaucoma
  • Prior glaucoma surgery in the study eye
  • Planned stand-alone goniotomy
  • Inability to comply with follow-up schedule

Treatment and study plan

Goniotomy

Procedure

Goniotomy opens the trabecular meshwork to lower intraocular pressure.

Primary outcomes

  1. Intraocular pressure

    Time frame: up to 6 months

    Eye pressure as measured by Goldmann applanation tonometry in mmHg

  2. Medications

    Time frame: up to 6 months

    number of medications to control intraocular pressure

  3. Visual Acuity

    Time frame: up to 6 months

    Measure of visual at each visit on Snellen acuity chart

Study contacts

Contact information is provided by the study sponsor or research team.

Calvin Robbins, MD

CONTACT

[email protected]

313-916-3245

David A Crandall, MD

CONTACT

[email protected]

248-661-5100

Sponsors and collaborators

Lead sponsor

Henry Ford Health System

Other

Registry information

Important dates

Study start
2026
Primary completion
2028
Study completion
2028
First posted
Feb 18, 2026
Registry last updated
Jun 11, 2026

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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