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OpenTrials
Completed

NCT Number: NCT01895686

Comparison of Gonioscopy With Cirrus and Visante

The aim of this study is to analyze similarities and evaluate interchangeability of Visante and Cirrus OCT (optical coherent tomography)and to compare agreement between gonioscopy and the two systems for evaluation of anterior segment parameters.

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Key information

Age range

18 year and older

Sex eligibility

All sexes

Study type

Observational

Primary location

Wills Eye Hospital, Glaucoma Service

Philadelphia, Pennsylvania, 19107, United States

About this study

All participants underwent routine ophthalmic examination by their physician. Three independent examiners performed gonioscopy using Spaeth Gonioscopic Grading System. Findings were recorded independently along with risk assessment of angle being closed as: high, medium, and low or no risk. Patient information was not available to doctor during gonioscopy. One eye of each patient was imaged using both Visante and Cirrus OCT. Imaging was performed under scotopic and photopic conditions and obtained from horizontal (3:00 and 9:00 o'clock) and vertical (6:00 and 12:00 o'clock) meridians. The same experienced independent examiner performed all Cirrus measurements. Visante was performed by 3 trained technicians using same protocol.

OCT images were exported and masked to be evaluated for presence of open or closed anterior chamber angle. Masked images were presented with no other patient information available to two examiners with glaucoma training working together to score on basis of iridocorneal angle as, closed (0 degree), high possibility (10 degree), medium risk (20 degree), and low or no risk (> 30 degree).

Who can participate

Healthy volunteers accepted: No

Only the study team can determine whether someone qualifies for participation.

Inclusion criteria

  • 18 years of age and older with open angle, narrow angle and angle closure

Exclusion criteria

  • All lasers or intraocular surgery (cataract, glaucoma, retina, cornea)

Treatment and study plan

Primary outcomes

  1. anterior angle measurement

    Time frame: 1 day

    comparison of AS assessment by Cirrus, Visante, gonioscopies

Sponsors and collaborators

Lead sponsor

Wills Eye

Other

Registry information

Official study title

Comparison of Visante and Cirrus Optical Coherent Tomography for Assessment of the Anterior Segment

Acronym: ASOCT

Important dates

Study start
2011
Primary completion
2012
Study completion
2012
First posted
Jul 10, 2013
Registry last updated
Apr 2, 2018

OpenTrials presents study information sourced from ClinicalTrials.gov. The official registry record should be consulted for the latest information.

View the official ClinicalTrials.gov record (opens in a new tab)

This listing is for discovery and informational purposes only. It is not medical advice, does not guarantee that a study is recruiting, and does not determine eligibility. Contact the study team and a qualified healthcare professional when considering participation.

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